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1/14/2018 5:07:58 AM | Browse: 1589 | Download: 2290
Publication Name World Journal of Gastroenterology
Manuscript ID 36846
Country China
Received
2017-10-27 02:03
Peer-Review Started
2017-10-27 06:25
First Decision by Editorial Office Director
2017-11-14 19:45
Return for Revision
2017-11-16 11:53
Revised
2017-11-18 14:47
Publication Fee Transferred
Second Decision by Editor
2017-12-04 09:15
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2017-12-04 19:52
Articles in Press
2017-12-04 19:52
Edit the Manuscript by Language Editor
2017-12-08 04:40
Typeset the Manuscript
2017-12-27 14:15
Publish the Manuscript Online
2018-01-14 05:07
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Predictive and prognostic value of serum AFP level and its dynamic changes for serum AFP elevated advanced gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Ya-Kun Wang, Lin Shen, Xi Jiao and Xiao-Tian Zhang
ORCID
Author(s) ORCID Number
Ya-Kun Wang http://orcid.org/0000-0001-5579-2998
Lin Shen http://orcid.org/0000-0002-1205-049X
Xi Jiao http://orcid.org/0000-0002-5588-5657
Xiao-Tian Zhang http://orcid.org/0000-0001-5267-7871
Funding Agency and Grant Number
Corresponding Author Xiao-Tian Zhang, MD, Professor, Department of Gastrointestinal Oncology, Peking University Cancer Hospital & Institute, No. 52, Fucheng Road, Haidian District, Beijing 100142, China. zhangxiaotianmed@163.com
Key Words Alpha-fetoprotein; AFP-producing gastric cancer; Predictive factor; Prognostic factor; Triplet regimen
Core Tip Alpha-fetoprotein (AFP)-producing gastric cancer is a rare and aggressive subtype of gastric cancer, characterized by frequent liver metastasis and poor prognosis. We measured AFP and its changes over time during treatment, revealing that AFP, as a biomarker of AFP elevated advanced gastric cancer (AFPAGC), is significantly associated with response to chemotherapy. And declines in AFP after chemotherapy are considered related to good prognosis for AFPAGC. We finally attempted to find an optimal treatment regimen for AFPAGC, and suggest for those with markedly elevated AFP, triplet regimen may be a better choice.
Publish Date 2018-01-14 05:07
Citation Wang YK, Zhang XT, Jiao X, Shen L. Predictive and prognostic value of serum AFP level and its dynamic changes in advanced gastric cancer patients with elevated serum AFP. World J Gastroenterol 2018; 24(2): 266-273
URL http://www.wjgnet.com/1007-9327/full/v24/i2/266.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i2.266
Full Article (PDF) WJG-24-266.pdf
Full Article (Word) WJG-24-266.doc