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12/27/2017 11:08:07 AM | Browse: 413 | Download: 357
Publication Name World Journal of Gastroenterology
Manuscript ID 36967
Country/Territory Brazil
Received
2017-10-31 01:11
Peer-Review Started
2017-10-31 07:58
To Make the First Decision
2017-11-22 01:01
Return for Revision
2017-11-27 06:59
Revised
2017-12-04 19:00
Second Decision
2017-12-12 08:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-12-12 19:44
Articles in Press
2017-12-12 19:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-12-19 02:58
Publish the Manuscript Online
2017-12-27 11:08
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Editorial
Article Title Serum levels of angiotensin converting enzyme as a biomarker of liver fibrosis
Manuscript Source Invited Manuscript
All Author List Aline Silva Miranda and Ana Cristina Simoes e Silva
ORCID
Author(s) ORCID Number
Aline Silva Miranda http://orcid.org/0000-0003-2811-7924
Ana Cristina Simoes e Silva http://orcid.org/0000-0001-9222-3882
Funding Agency and Grant Number
Funding Agency Grant Number
CNPq 460334/2014-0
FAPEMIG CDS - PPM-00555-15
2016 NARSAD Young Investigator Grant Awardee from the Brain and Behavior Research Foundation 25414
Corresponding Author Ana Cristina Simoes e Silva, MD, PhD, Professor, Research Scientist, Departament of Pediatrics, Pediatric Nephrology Unit, Universidade Federal de Minas Gerais, Faculty of Medicine, UFMG. Alfredo Balena Avenue, Number 190, 2nd floor, Room # 281, Belo Horizonte 30130-100, Minas Geris, Brazil. acssilva@hotmail.com
Key Words Renin angiotensin system; Angiotensin converting enzyme; Angiotensin II; Angiotensin-(1-7); Chronic hepatitis B; Hepatic cirrhosis; Liver fibrosis
Core Tip The therapeutic intervention for patients with chronic hepatitis B (CHB) frequently relies on the pathological classification of liver fibrosis severity in biopsy. The establishment of non-invasive and accurate methods to detect reversible stages of liver fibrosis is still a challenge. High serum levels of angiotensin converting enzyme seem to better predict liver intermediate fibrosis than other classical fibrotic markers. Non-invasive methods to detect with very good accuracy intermediate stages of liver fibrosis may permit the introduction and/or evaluation of treatments during reversible stages of the disease. Further studies are urgently necessary to fully clarify the role of RAS components in liver disease.
Publish Date 2017-12-27 11:08
Citation Miranda AS, Simões e Silva AC. Serum levels of angiotensin converting enzyme as a biomarker of liver fibrosis. World J Gastroenterol 2017; 23(48): 8439-8442
Url http://www.wjgnet.com/1007-9327/full/v23/i48/8439.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i48.8439
Full Article (PDF) WJG-23-8439.pdf
Full Article (Word) WJG-23-8439.doc
Manuscript File 36967-Review.docx
Answering Reviewers 36967-Answering reviewers.pdf
Audio Core Tip 36967-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 36967-Conflict-of-interest statement.pdf
Copyright License Agreement 36967-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 36967-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 36967-Language certificate.pdf
Peer-review Report 36967-Peer-review(s).pdf
Scientific Misconduct Check 36967-Scientific misconduct check.pdf
Scientific Editor Work List 36967-Scientific editor work list.pdf