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Articles Published Processes
1/8/2018 2:29:32 AM | Browse: 867 | Download: 1157
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Received |
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2017-11-06 20:57 |
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Peer-Review Started |
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2017-11-09 02:58 |
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To Make the First Decision |
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2017-11-30 01:19 |
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Return for Revision |
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2017-12-01 06:03 |
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Revised |
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2017-12-10 12:51 |
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Second Decision |
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2017-12-14 10:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-12-28 19:49 |
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Articles in Press |
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2017-12-28 19:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-01-05 03:51 |
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Publish the Manuscript Online |
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2018-01-08 02:29 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Review |
| Article Title |
Immunoglobulin G4-related kidney diseases: An updated review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Maurizio Salvadori and Aris Tsalouchos |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Maurizio Salvadori, MD, Professor, Renal Unit, Careggi University Hospital, viale Pieraccini 18, 50139, Florence 50139, Italy. maurizio.salvadori1@gmail.com |
| Key Words |
Immunoglobulin G4-related disease; Storiform fibrosis; Lymphoplasmacytic infiltration; Tubulointerstitial nephritis; Steroid treatment; B cell depleting agents |
| Core Tip |
Immunoglobulin G4-related disease (IgG4-RD) is a recently recognized clinical entity that often involves multiple organs; it is characterized by high levels of serum immunoglobulin G4, dense infiltration of IgG4+ cells, and storiform fibrosis. Cellular immunity, particularly T cell-mediated immunity, has been implicated in the pathogenesis of IgG4-RD. The most frequent renal manifestations of IgG4-RD are IgG4-related tubulointerstitial nephritis, membranous glomerulonephropathy and obstructive nephropathy secondary to urinary tract obstruction due to IgG4-related retroperitoneal fibrosis. In IgG4-membranous glomerulopathy, proteinuria can be in the nephrotic range. Steroid treatment is the first-line therapy. For relapsing or refractory cases, immunosuppressants could be combined with steroids. |
| Publish Date |
2018-01-08 02:29 |
| Citation |
Salvadori M, Tsalouchos A. Immunoglobulin G4-related kidney diseases: An updated review. World J Nephrol 2018; 7(1): 29-40 |
| URL |
http://www.wjgnet.com/2220-6124/full/v7/i1/29.htm |
| DOI |
http://dx.doi.org/10.5527/wjn.v7.i1.29 |
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