Publication Name	World Journal of Nephrology
Manuscript ID	37042
Country	Italy

Received	2017-11-06 20:57
Peer-Review Started	2017-11-09 02:58
First Decision by Editorial Office Director	2017-11-29 21:37
Return for Revision	2017-12-01 06:03
Revised	2017-12-10 12:51
Publication Fee Transferred
Second Decision by Editor	2017-12-14 10:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2017-12-28 19:49
Articles in Press	2017-12-28 19:49
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-01-05 03:51
Publish the Manuscript Online	2018-01-08 02:29

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Urology & Nephrology
Manuscript Type	Review
Article Title	Immunoglobulin G4-related kidney diseases: An updated review
Manuscript Source	Invited Manuscript
All Author List	Maurizio Salvadori and Aris Tsalouchos
ORCID	Author(s) ORCID Number Maurizio Salvadori http://orcid.org/0000-0003-1503-2681 Aris Tsalouchos http://orcid.org/0000-0002-8565-4059
Funding Agency and Grant Number
Corresponding Author	Maurizio Salvadori, MD, Professor, Renal Unit, Careggi University Hospital, viale Pieraccini 18, 50139, Florence 50139, Italy. maurizio.salvadori1@gmail.com
Key Words	Immunoglobulin G4-related disease; Storiform fibrosis; Lymphoplasmacytic infiltration; Tubulointerstitial nephritis; Steroid treatment; B cell depleting agents
Core Tip	Immunoglobulin G4-related disease (IgG4-RD) is a recently recognized clinical entity that often involves multiple organs; it is characterized by high levels of serum immunoglobulin G4, dense infiltration of IgG4+ cells, and storiform fibrosis. Cellular immunity, particularly T cell-mediated immunity, has been implicated in the pathogenesis of IgG4-RD. The most frequent renal manifestations of IgG4-RD are IgG4-related tubulointerstitial nephritis, membranous glomerulonephropathy and obstructive nephropathy secondary to urinary tract obstruction due to IgG4-related retroperitoneal fibrosis. In IgG4-membranous glomerulopathy, proteinuria can be in the nephrotic range. Steroid treatment is the first-line therapy. For relapsing or refractory cases, immunosuppressants could be combined with steroids.
Publish Date	2018-01-08 02:29
Citation	Salvadori M, Tsalouchos A. Immunoglobulin G4-related kidney diseases: An updated review. World J Nephrol 2018; 7(1): 29-40
URL	http://www.wjgnet.com/2220-6124/full/v7/i1/29.htm
DOI	http://dx.doi.org/10.5527/wjn.v7.i1.29

Full Article (PDF)	WJN-7-29.pdf
Full Article (Word)	WJN-7-29.doc
Manuscript File	37042-Review.docx
Answering Reviewers	37042-Answering reviewers.pdf
Audio Core Tip	37042-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	37042-Conflict-of-interest statement.pdf
Copyright License Agreement	37042-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	37042-Language certificate.pdf
Peer-review Report	37042-Peer-review(s).pdf
Scientific Misconduct Check	37042-Scientific misconduct check.pdf
Scientific Editor Work List	37042-Scientific editor work list.pdf