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Articles Published Processes
1/31/2018 1:17:45 AM | Browse: 802 | Download: 1466
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Received |
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2017-11-09 09:24 |
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Peer-Review Started |
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2017-11-09 09:43 |
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To Make the First Decision |
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2017-11-22 01:05 |
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Return for Revision |
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2017-11-27 07:28 |
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Revised |
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2017-12-05 16:09 |
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Second Decision |
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2017-12-12 08:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2017-12-12 19:39 |
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Articles in Press |
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2017-12-12 19:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-12-24 04:44 |
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Typeset the Manuscript |
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2018-01-26 05:55 |
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Publish the Manuscript Online |
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2018-01-31 01:17 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Case Control Study |
| Article Title |
Impact of SNP-SNP interactions of DNA repair gene ERCC5 and metabolic gene GSTP1 on gastric cancer/atrophic gastritis risk in a Chinese population
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Liang Sang, Zhi Lv, Li-Ping Sun, Qian Xu and Yuan Yuan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Science and Technology Support Program |
2015BAI13B07 |
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| Corresponding Author |
Yuan Yuan, MD, Professor, Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Hospital of China Medical University, Nanjing North ST., Shenyang 110001, China. yuanyuan@cmu.edu.cn |
| Key Words |
Excision repair cross complementing group 5; Glutathione S-transferase pi 1; Atrophic gastritis; Gastric cancer; Single nucleotide polymorphisms |
| Core Tip |
We detected seven excision repair cross complementing group 5 (ERCC5) single nucleotide polymorphisms (SNPs) and a glutathione S-transferase pi1 (GSTP1) SNP using the Sequenom MassARRAY platform in a Chinese population and used them to investigate their interactions and their effects on atrophic gastritis and gastric cancer risk. The results showed a multifarious interaction between the DNA repair gene ERCC5 SNPs (rs2094258 and rs873601) and the metabolic gene GSTP1 rs1695. In addition, the cumulative effect of one pairwise interaction (ERCC5 rs873601-GSTP1 rs1695) was associated with an increased atrophic gastritis risk in the case of negative H. pylori status when the modification effect of H. pylori infection was evaluated. |
| Publish Date |
2018-01-31 01:17 |
| Citation |
Sang L, Lv Z, Sun LP, Xu Q, Yuan Y. Impact of SNP-SNP interactions of DNA repair gene ERCC5 and metabolic gene GSTP1 on gastric cancer/atrophic gastritis risk in a Chinese population. World J Gastroenterol 2018; 24(5): 602-612 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i5/602.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i5.602 |
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