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Articles Published Processes
1/31/2018 1:17:45 AM | Browse: 928 | Download: 2049
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Received |
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2017-11-09 09:24 |
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Peer-Review Started |
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2017-11-09 09:43 |
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To Make the First Decision |
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2017-11-22 01:05 |
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Return for Revision |
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2017-11-27 07:28 |
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Revised |
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2017-12-05 16:09 |
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Second Decision |
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2017-12-12 08:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-12-12 19:39 |
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Articles in Press |
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2017-12-12 19:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2017-12-24 04:44 |
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Typeset the Manuscript |
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2018-01-26 05:55 |
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Publish the Manuscript Online |
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2018-01-31 01:17 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Case Control Study |
| Article Title |
Impact of SNP-SNP interactions of DNA repair gene ERCC5 and metabolic gene GSTP1 on gastric cancer/atrophic gastritis risk in a Chinese population
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Liang Sang, Zhi Lv, Li-Ping Sun, Qian Xu and Yuan Yuan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Science and Technology Support Program |
2015BAI13B07 |
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| Corresponding Author |
Yuan Yuan, MD, Professor, Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Hospital of China Medical University, Nanjing North ST., Shenyang 110001, Liaoning Province, China. yuanyuan@cmu.edu.cn |
| Key Words |
Excision repair cross complementing group 5; Glutathione S-transferase pi 1; Atrophic gastritis; Gastric cancer; Single nucleotide polymorphisms |
| Core Tip |
We detected seven excision repair cross complementing group 5 (ERCC5) single nucleotide polymorphisms (SNPs) and a glutathione S-transferase pi1 (GSTP1) SNP using the Sequenom MassARRAY platform in a Chinese population and used them to investigate their interactions and their effects on atrophic gastritis and gastric cancer risk. The results showed a multifarious interaction between the DNA repair gene ERCC5 SNPs (rs2094258 and rs873601) and the metabolic gene GSTP1 rs1695. In addition, the cumulative effect of one pairwise interaction (ERCC5 rs873601-GSTP1 rs1695) was associated with an increased atrophic gastritis risk in the case of negative H. pylori status when the modification effect of H. pylori infection was evaluated. |
| Publish Date |
2018-01-31 01:17 |
| Citation |
Sang L, Lv Z, Sun LP, Xu Q, Yuan Y. Impact of SNP-SNP interactions of DNA repair gene ERCC5 and metabolic gene GSTP1 on gastric cancer/atrophic gastritis risk in a Chinese population. World J Gastroenterol 2018; 24(5): 602-612 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i5/602.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i5.602 |
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