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Articles Published Processes
1/26/2018 8:09:36 AM | Browse: 1112 | Download: 1697
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Received |
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2017-11-22 00:44 |
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Peer-Review Started |
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To Make the First Decision |
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2017-12-07 00:24 |
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Return for Revision |
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2017-12-07 01:56 |
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Revised |
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2017-12-15 07:33 |
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Second Decision |
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2017-12-28 10:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-01-09 05:57 |
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Articles in Press |
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2018-01-09 05:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-01-25 03:14 |
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Publish the Manuscript Online |
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2018-01-26 08:09 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Collagen proportionate area correlates to hepatic venous pressure gradient in non-abstinent cirrhotic patients with alcoholic liver disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Sophie Restellini, Nicolas Goossens, Sophie Clement, Nicolas Lanthier, Francesco Negro, Laura Rubbia-Brandt and Laurent Spahr |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Laurent Spahr, MD, Professor, Division of Gastroenterology and Hepatology, University Hospitals of Geneva, 4, Rue Gabrielle Perret Gentil, Geneva 1211, Switzerland. laurent.spahr@hcuge.ch |
| Key Words |
Fibrosis; Hepatic venous pressure gradient; Cirrhosis; Chronic advanced liver disease; Collagen proportionate area |
| Core Tip |
This is the first study exploring the relationships between fibrosis density assessed by collagen proportionate area (CPA) in liver biopsy, hepatic venous pressure gradient (HVPG) and development of clinical manifestations of portal hypertension in patients with chronic advanced alcoholic liver disease addressed for liver investigations. The results suggest a positive correlation between high fibrosis density and the HVPG only in active drinkers. HVPG, but not CPA, predicts clinical events in active alcohol drinkers pointing to the role of alcohol as a modulator of portal hypertension. |
| Publish Date |
2018-01-26 08:09 |
| Citation |
Restellini S, Goossens N, Clément S, Lanthier N, Negro F, Rubbia-Brandt L, Spahr L. Collagen proportionate area correlates to hepatic venous pressure gradient in non-abstinent cirrhotic patients with alcoholic liver disease. World J Hepatol 2018; 10(1): 73-81 |
| URL |
http://www.wjgnet.com/1948-5182/full/v10/i1/73.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v10.i1.73 |
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