Publication Name	World Journal of Clinical Oncology
Manuscript ID	37221
Country	Peru

Received	2017-11-22 17:16
Peer-Review Started
To Make the First Decision	2017-12-07 00:25
Return for Revision	2017-12-07 01:14
Revised	2017-12-19 14:53
Second Decision	2017-12-28 10:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-02-05 23:24
Articles in Press	2018-02-05 23:24
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-02-13 20:15
Typeset the Manuscript	2018-03-26 14:38
Publish the Manuscript Online	2018-04-11 01:34

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Observational Study
Article Title	Clinicopathological predictors of long-term benefit in breast cancer treated with neoadjuvant chemotherapy
Manuscript Source	Unsolicited Manuscript
All Author List	Marco Galvez, Carlos A Castaneda, Joselyn Sanchez, Miluska Castillo, Lia Pamela Rebaza, Gabriela Calderon, Miguel De La Cruz, Jose Manuel Cotrina, Julio Abugattas, Jorge Dunstan, Henry Guerra, Omar Mejia and Henry L Gomez
ORCID	Author(s) ORCID Number Marco Galvez http://orcid.org/0000-0002-1408-4474 Carlos A Castaneda http://orcid.org/0000-0001-6200-0856 Joselyn Sanchez http://orcid.org/0000-0002-6764-4180 Miluska Castillo http://orcid.org/0000-0002-0111-3176 Lia Pamela Rebaza http://orcid.org/0000-0002-8327-6146 Gabriela Calderon http://orcid.org/0000-0002-2500-8493 Miguel De La Cruz http://orcid.org/0000-0003-4405-3991 Jose Manuel Cotrina http://orcid.org/0000-0002-8330-803X Julio Abugattas http://orcid.org/0000-0002-9806-0989 Jorge Dunstan http://orcid.org/0000-0002-4148-6858 Henry Guerra http://orcid.org/0000-0002-4894-5631 Omar Mejia http://orcid.org/0000-0002-6196-3594 Henry L Gomez http://orcid.org/0000-0003-2660-1843
Funding Agency and Grant Number
Corresponding Author	Carlos A Castaneda, MD, MSc, Assistant Professor, Medical Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, Lima 15038, Peru. ccastaneda@inen.sld.pe
Key Words	Breast cancer; Subtype; Tumor-infiltrating lymphocytes; Neoadjuvant therapy; Pathological complete response; Survival
Core Tip	The authors evaluated a series of 435 breast cancer (BC) patients who received neoadjuvant chemotherapy. They evaluated the association between stromal tumor-infiltrating lymphocytes levels and pCR in preneoadjuvant chemotherapy samples according to molecular subtypes. The results confirm differences in the predictive and prognostic role of stromal tumorinfiltrating lymphocytes and pathological complete response depending on the tumor subtype. Additionally, the authors evaluate the value of traditional prognostic features in every BC subset. The results increase the understanding of biomarkers in the heterogeneous scenario of BC.
Publish Date	2018-04-11 01:34
Citation	Galvez M, Castaneda CA, Sanchez J, Castillo M, Rebaza LP, Calderon G, De La Cruz M, Cotrina JM, Abugattas J, Dunstan J, Guerra H, Mejia O, Gomez HL. Clinicopathological predictors of long-term benefit in breast cancer treated with neoadjuvant chemotherapy. World J Clin Oncol 2018; 9(2): 33-41
URL	http://www.wjgnet.com/2218-4333/full/v9/i2/33.htm
DOI	http://dx.doi.org/10.5306/wjco.v9.i2.33

Full Article (PDF)	WJCO-9-33.pdf
Full Article (Word)	WJCO-9-33.doc
Manuscript File	37221-Review.docx
Answering Reviewers	37221-Answering reviewers.pdf
Audio Core Tip	37221-Audio core tip.mp3
Biostatistics Review Certificate	37221-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	37221-Conflict-of-interest statement.pdf
Copyright License Agreement	37221-Copyright assignment.PDF
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	37221-Approved-Grant-Application-Form(s)-or-Funding-Agency-Copy-of-any-Approval-Document(s)-revision.pdf
Signed Informed Consent Form(s) or Document(s)	37221-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	37221-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	37221-Non-Native Speakers of English Editing Certificate.pdf
Supplementary Material	37221-Supplementary-Material-revision.pdf
Peer-review Report	37221-Peer-review(s).pdf
Scientific Misconduct Check	37221-Scientific misconduct check.pdf
Scientific Editor Work List	37221-Scientific editor work list.pdf