Publication Name	World Journal of Clinical Cases
Manuscript ID	37265
Country	Switzerland

Received	2018-01-08 19:04
Peer-Review Started	2018-01-09 02:23
To Make the First Decision	2018-01-25 08:58
Return for Revision	2018-01-29 03:25
Revised	2018-02-06 21:54
Second Decision	2018-02-28 08:18
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-03-07 21:25
Articles in Press	2018-03-07 21:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-04-11 15:51
Publish the Manuscript Online	2018-04-16 09:47

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Medicine, Research & Experimental
Manuscript Type	Retrospective Cohort Study
Article Title	High prevalence of cholestasis, with increased conjugated bile acids in inflammatory bowel diseases patients
Manuscript Source	Unsolicited Manuscript
All Author List	Marc Girardin, Antoine Hadengue and Jean Louis Frossard
ORCID	Author(s) ORCID Number Marc Girardin http://orcid.org/0000-0002-5567-2635 Antoine Hadengue http://orcid.org/0000-0002-3497-954X Jean Louis Frossard http://orcid.org/0000-0002-6309-1603
Funding Agency and Grant Number
Corresponding Author	Marc Girardin, MD, Attending Doctor, Service of Gastroenterology and Hepatology, Geneva University Hospital, Rue Gabrielle-Perret Gentil 4, Geneva 1211, Switzerland. marc.girardin@hcuge.ch
Key Words	Lipid; Liver; Crohn’s disease; Ulcerative colitis; Cholestasis
Core Tip	Inflammatory bowel diseases (IBDs) are often associated with cholestasis. This study shows that the prevalence of cholestasis in IBD patients is high at 7%. Current smoking seems to be a protective factor against cholestasis, maybe reflecting a different gut function than in nonsmokers. Ileal disease was more often associated with elevated non conjugated bile acids levels. Colonic disease was characterized by higher conjugated bile acids levels.
Publish Date	2018-04-16 09:47
Citation	Girardin M, Hadengue A, Frossard JL; the Swiss IBD Cohort Study Group. High prevalence of cholestasis, with increased conjugated bile acids in inflammatory bowel diseases patients. World J Clin Cases 2018; 6(4): 44-53
URL	http://www.wjgnet.com/2307-8960/full/v6/i4/44.htm
DOI	http://dx.doi.org/10.12998/wjcc.v6.i4.44

Full Article (PDF)	WJCC-6-44.pdf
Full Article (Word)	WJCC-6-44.doc
STROBE Statement	37265-STROBE statement.pdf
Manuscript File	37265-Review.docx
Answering Reviewers	37265-Answering reviewers.pdf
Audio Core Tip	37265-Audio core tip.mp3
Biostatistics Review Certificate	37265-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	37265-Conflict-of-interest statement.pdf
Copyright License Agreement	37265-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	37265-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	37265-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	37265-Language certificate.pdf
Supplementary Material	37265-Supplementary material.pdf
Peer-review Report	37265-Peer-review(s).pdf
Scientific Misconduct Check	37265-Scientific misconduct check.pdf
Scientific Editor Work List	37265-Scientific editor work list.pdf