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2/9/2018 7:24:29 AM | Browse: 530 | Download: 383
Publication Name World Journal of Gastroenterology
Manuscript ID 37288
Country/Territory Spain
2017-12-02 14:24
Peer-Review Started
2017-12-02 17:23
To Make the First Decision
2017-12-20 07:49
Return for Revision
2017-12-21 03:51
2018-01-15 16:59
Second Decision
2018-01-18 10:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-01-18 15:08
Articles in Press
2018-01-18 15:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-01-27 20:32
Typeset the Manuscript
2018-02-08 08:03
Publish the Manuscript Online
2018-02-09 07:24
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Translational pancreatic cancer research: A comparative study on patient-derived xenograft models
Manuscript Source Unsolicited Manuscript
All Author List Mercedes Rubio-Manzanares Dorado, Luis Miguel Marín Gómez, Daniel Aparicio Sánchez, Sheila Pereira Arenas, Juan Manuel Praena-Fernández, Juan Jose Borrero Martín, Francisco Farfán López, Miguel Ángel Gómez Bravo, Jordi Muntané Relat and Javier Padillo Ruiz
Author(s) ORCID Number
Mercedes Rubio-Manzanares Dorado http://orcid.org/0000-0002-0433-1881
Luis Miguel Marín Gómez http://orcid.org/0000-0003-3087-7228
Daniel Aparicio Sánchez http://orcid.org/0000-0001-7061-345X
Sheila Pereira Arenas http://orcid.org/0000-0002-5009-5699
Juan Manuel Praena-Fernández http://orcid.org/0000-0001-5728-1024
Juan Jose Borrero Martín http://orcid.org/0000-0001-8292-8838
Francisco Farfán López http://orcid.org/0000-0002-5555-4655
Miguel Ángel Gómez Bravo http://orcid.org/0000-0002-5155-3508
Jordi Muntané Relat http://orcid.org/0000-0002-6744-1121
Javier Padillo Ruiz http://orcid.org/0000-0002-1220-0822
Funding Agency and Grant Number
Funding Agency Grant Number
the Andalusian Public Foundation for the Management of Health Research in Seville (FISEVI)
Corresponding author Mercedes Rubio-Manzanares Dorado, MD, PhD, Staff Physician, General Surgeon, Department of Hepatobiliary and Pancreatic Surgery, Virgen del Rocio Universitary Hospital, Manuel Siurot St, Seville 41013, Spain. mercedesrmd@gmail.com
Keywords Immunohistological analysis; Pancreatic cancer; Patient-derived xenograft; Animal model; Nude mice
Core Tip Several investigations have established patient-derived xenograft models for breast, renal, head and neck cancer, and hepatocellular tumours. Some of these models have predicted the clinical response of a specific type of tumour to different chemotherapeutic agents. However, the morphological and histological features of human pancreatic cancer xenografts in experimental models have been poorly studied. In the present study, the effectiveness of three experimental models based on the implantation of patient pancreatic cancer in three different locations (subcutaneous, intraperitoneal and pancreatic) have been assessed for the first time.
Publish Date 2018-02-09 07:24
Citation Rubio-Manzanares Dorado M, Marín Gómez LM, Aparicio Sánchez D, Pereira Arenas S, Praena-Fernández JM, Borrero Martín JJ, Farfán López F, Gómez Bravo MÁ, Muntané Relat J, Padillo Ruiz J. Translational pancreatic cancer research: A comparative study on patient-derived xenograft models. World J Gastroenterol 2018; 24(7): 794-809
Url http://www.wjgnet.com/1007-9327/full/v24/i7/794.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i7.794
Full Article (PDF) WJG-24-794.pdf
Full Article (Word) WJG-24-794.doc
Manuscript File 37288-Review.docx
Answering Reviewers 37288-Answering reviewers.pdf
Audio Core Tip 37288-Audio core tip.aiff
Biostatistics Review Certificate 37288-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 37288-Conflict-of-interest statement.pdf
Copyright License Agreement 37288-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 37288-Grant Application Form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 37288-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 37288-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 37288-Language certificate.pdf
Peer-review Report 37288-Peer-review(s).pdf
Scientific Misconduct Check 37288-Scientific misconduct check.pdf
Scientific Editor Work List 37288-Scientific editor work list.docx