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Publication Name World Journal of Hepatology
Manuscript ID 37335
Country/Territory Türkiye
Received
2017-12-03 03:01
Peer-Review Started
To Make the First Decision
2017-12-04 01:26
Return for Revision
2017-12-04 02:30
Revised
2017-12-07 07:05
Second Decision
2017-12-14 10:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-12-29 17:43
Articles in Press
2017-12-29 17:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-01-18 14:41
Publish the Manuscript Online
2018-01-26 08:09
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Current state and clinical outcome in Turkish patients with hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Omer Ekinci, Bulent Baran, Asli Cifcibasi Ormeci, Ozlem Mutluay Soyer, Suut Gokturk, Sami Evirgen, Arzu Poyanli, Mine Gulluoglu, Filiz Akyuz, Cetin Karaca, Kadir Demir, Fatih Besisik and Sabahattin Kaymakoglu
ORCID
Author(s) ORCID Number
Omer Ekinci http://orcid.org/0000-0002-4636-3590
Bulent Baran http://orcid.org/0000-0001-7966-2346
Asli Cifcibasi Ormeci http://orcid.org/0000-0001-6297-8045
Ozlem Mutluay Soyer http://orcid.org/0000-0003-2768-8354
Suut Gokturk http://orcid.org/0000-0003-1664-3265
Sami Evirgen http://orcid.org/0000-0001-6920-777X
Arzu Poyanli http://orcid.org/0000-0002-8851-1109
Mine Gulluoglu http://orcid.org/0000-0002-3967-0779
Filiz Akyuz http://orcid.org/0000-0001-7498-141X
Cetin Karaca http://orcid.org/0000-0001-5574-0602
Kadir Demir http://orcid.org/0000-0002-5226-3705
Fatih Besisik http://orcid.org/0000-0001-5184-376X
Sabahattin Kaymakoglu http://orcid.org/0000-0003-4910-249X
Funding Agency and Grant Number
Corresponding Author Sabahattin Kaymakoglu, MD, Professor, Department of Gastroenterohepatology, Istanbul University, Istanbul Faculty of Medicine, Capa, Istanbul, Istanbul 34093, Türkiye. sabahattin.kaymakoglu@istanbul.edu.tr
Key Words Hepatocellular carcinoma; Cirrhosis; Alfa-fetoprotein; Prognosis; Treatment; Survival
Core Tip Hepatocellular carcinoma is a leading cause of cancer-related death with curative treatment options limited to orthotopic liver transplantation, surgical resection and local ablation. Our study confirmed that liver functional reserve, tumor extension and alfa-fetoprotein level are among the most important determinants of patient survival. Survival benefit of non-curative treatments including transarterial chemoembolization and Yttrium-90 radioembolization remains an area of uncertainty. In this study we showed that transarterial chemoembolization and Yttrium-90 radioembolization provided a significant and comparable survival benefit in patients with hepatocellular carcinoma in the real-life setting. We concluded that primary modality of treatment for hepatocellular carcinoma is a major determinant of patient survival that should be incorporated while estimating prognosis.
Publish Date 2018-01-26 08:09
Citation Ekinci O, Baran B, Ormeci AC, Soyer OM, Gokturk S, Evirgen S, Poyanli A, Gulluoglu M, Akyuz F, Karaca C, Demir K, Besisik F, Kaymakoglu S. Current state and clinical outcome in Turkish patients with hepatocellular carcinoma. World J Hepatol 2018; 10(1): 51-61
URL http://www.wjgnet.com/1948-5182/full/v10/i1/51.htm
DOI http://dx.doi.org/10.4254/wjh.v10.i1.51
Full Article (PDF) WJH-10-51.pdf
Full Article (Word) WJH-10-51.doc
Manuscript File 37335-Review.docx
Answering Reviewers 37335-Answering reviewers.pdf
Audio Core Tip 37335-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 37335-Conflict-of-interest statement.pdf
Copyright License Agreement 37335-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 37335-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 37335-Institutional review board statement.pdf
Supplementary Material 37335-Supplementary material.pdf
Peer-review Report 37335-Peer-review(s).pdf
Scientific Misconduct Check 37335-Scientific misconduct check.pdf
Scientific Editor Work List 37335-Scientific editor work list.pdf