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4/4/2018 1:15:45 PM | Browse: 1073 | Download: 1313
Publication Name World Journal of Gastroenterology
Manuscript ID 37348
Country/Territory Germany
Received
2017-12-06 17:02
Peer-Review Started
2017-12-06 18:59
To Make the First Decision
2018-01-17 01:24
Return for Revision
2018-01-18 06:08
Revised
2018-02-21 16:28
Second Decision
2018-03-02 07:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-03-03 03:41
Articles in Press
2018-03-03 03:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-04-03 05:49
Publish the Manuscript Online
2018-04-04 13:15
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Potential triggering factors of acute liver failure as a first manifestation of autoimmune hepatitis-a single center experience of 52 adult patients
Manuscript Source Unsolicited Manuscript
All Author List Matthias Buechter, Paul Manka, Falko M Heinemann, Monika Lindemann, Martin Schlattjan, Ali Canbay, Guido Gerken and Alisan Kahraman
ORCID
Author(s) ORCID Number
Matthias Buechter http://orcid.org/0000-0003-3394-5492
Paul Manka http://orcid.org/0000-0001-8589-7280
Falko M Heinemann http://orcid.org/0000-0002-9642-1154
Monika Lindemann http://orcid.org/0000-0001-6708-4390
Martin Schlattjan http://orcid.org/0000-0001-6639-5568
Ali Canbay http://orcid.org/0000-0001-6069-7899
Guido Gerken http://orcid.org/0000-0001-6734-5001
Alisan Kahraman http://orcid.org/0000-0002-2823-6774
Funding Agency and Grant Number
Corresponding Author Alisan Kahraman, MD, Associate Professor, Department of Gastroenterology and Hepatology, University Hospital of Essen, Hufelandstr 55, Essen 45122, North-Rhine Westphalia, Germany. alisan.kahraman@uk-essen.de
Key Words Acute liver failure; Autoimmune hepatitis; Drug-induced liver injury; Triggering factors; MELD-score
Core Tip Autoimmune hepatitis is considered to mani­fest as a chronic disease. In few cases, the clinician is challenged with patients revealing acute liver failure as their first manifestation of autoimmune hepatitis (AIH). The aim of our study was to investigate features of especially these patients with focus on potential triggering factors. We identified triggering factors in half of our patients (26 out of 52 patients with acute liver failure within a total cohort of 565 AIH patients). These were drugs, viral infections, and surgery. Advanced age and high MELD-score were associated with lethal outcome. Consequently, the clinician would be well-advised to document these underlying conditions.
Publish Date 2018-04-04 13:15
Citation Buechter M, Manka P, Heinemann FM, Lindemann M, Baba HA, Schlattjan M, Canbay A, Gerken G, Kahraman A. Potential triggering factors of acute liver failure as a first manifestation of autoimmune hepatitis-a single center experience of 52 adult patients. World J Gastroenterol 2018; 24(13): 1410-1418
URL http://www.wjgnet.com/1007-9327/full/v24/i13/1410.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i13.1410
Full Article (PDF) WJG-24-1410.pdf
Full Article (Word) WJG-24-1410.doc
STROBE Statement 37348-STROBE-Statement-revision.pdf
Manuscript File 37348-Review.docx
Answering Reviewers 37348-Answering reviewers.pdf
Audio Core Tip 37348-Audio core tip.m4a
Biostatistics Review Certificate 37348-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 37348-Conflict-of-interest statement.pdf
Copyright License Agreement 37348-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 37348-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 37348-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 37348-Language certificate.pdf
Peer-review Report 37348-Peer-review(s).pdf
Scientific Misconduct Check 37348-Scientific misconduct check.pdf
Scientific Editor Work List 37348-Scientific editor work list.pdf