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Articles Published Processes
4/4/2018 1:15:45 PM | Browse: 1222 | Download: 1769
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Received |
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2017-12-06 17:02 |
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Peer-Review Started |
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2017-12-06 18:59 |
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To Make the First Decision |
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2018-01-17 01:24 |
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Return for Revision |
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2018-01-18 06:08 |
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Revised |
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2018-02-21 16:28 |
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Second Decision |
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2018-03-02 07:54 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-03-03 03:41 |
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Articles in Press |
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2018-03-03 03:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-04-03 05:49 |
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Publish the Manuscript Online |
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2018-04-04 13:15 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Potential triggering factors of acute liver failure as a first manifestation of autoimmune hepatitis-a single center experience of 52 adult patients
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Matthias Buechter, Paul Manka, Falko M Heinemann, Monika Lindemann, Martin Schlattjan, Ali Canbay, Guido Gerken and Alisan Kahraman |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Alisan Kahraman, MD, Associate Professor, Department of Gastroenterology and Hepatology, University Hospital of Essen, Hufelandstr 55, Essen 45122, North-Rhine Westphalia, Germany. alisan.kahraman@uk-essen.de |
Key Words |
Acute liver failure; Autoimmune hepatitis; Drug-induced liver injury; Triggering factors; MELD-score |
Core Tip |
Autoimmune hepatitis is considered to manifest as a chronic disease. In few cases, the clinician is challenged with patients revealing acute liver failure as their first manifestation of autoimmune hepatitis (AIH). The aim of our study was to investigate features of especially these patients with focus on potential triggering factors. We identified triggering factors in half of our patients (26 out of 52 patients with acute liver failure within a total cohort of 565 AIH patients). These were drugs, viral infections, and surgery. Advanced age and high MELD-score were associated with lethal outcome. Consequently, the clinician would be well-advised to document these underlying conditions. |
Publish Date |
2018-04-04 13:15 |
Citation |
Buechter M, Manka P, Heinemann FM, Lindemann M, Baba HA, Schlattjan M, Canbay A, Gerken G, Kahraman A. Potential triggering factors of acute liver failure as a first manifestation of autoimmune hepatitis-a single center experience of 52 adult patients. World J Gastroenterol 2018; 24(13): 1410-1418 |
URL |
http://www.wjgnet.com/1007-9327/full/v24/i13/1410.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v24.i13.1410 |
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