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Articles Published Processes
2/27/2018 5:35:21 AM | Browse: 1083 | Download: 2261
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Received |
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2017-12-21 08:23 |
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Peer-Review Started |
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2017-12-21 09:57 |
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First Decision by Editorial Office Director |
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2018-01-04 04:51 |
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Return for Revision |
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2018-01-04 09:26 |
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Revised |
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2018-01-11 10:22 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2018-01-18 11:04 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2018-01-18 15:06 |
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Articles in Press |
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2018-01-18 15:06 |
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Edit the Manuscript by Language Editor |
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2018-02-05 03:41 |
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Typeset the Manuscript |
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2018-02-23 10:37 |
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Publish the Manuscript Online |
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2018-02-27 05:35 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Intravoxel incoherent motion diffusion-weighted magnetic resonance imaging for predicting histological grade of hepatocellular carcinoma: Comparison with conventional diffusion-weighted imaging
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shao-Cheng Zhu, Yue-Hua Liu, Yi Wei, Lin-Lin Li, She-Wei Dou, Ting-Yi Sun and Da-Peng Shi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Shao-Cheng Zhu, MD, PhD, Chief Doctor, Professor, Department of Radiology, Henan Provincial People’s Hospital, No. 7, Weiwu Road, Zhengzhou 450003, Henan Province, China. 104753150948@vip.henu.edu.cn |
| Key Words |
Intravoxel incoherent motion; Diffusion-weighted imaging; Hepatocellular carcinoma; Pathological differentiation grade |
| Core Tip |
Intravoxel incoherent motion (IVIM)-based diffusion-weighted imaging (DWI) can yield diffusion and perfusion information simultaneously. The aims of this study were to compare IVIM-derived parameters with conventional DWI parameters for predicting the histological grade of hepatocellular carcinomas (HCCs) and to evaluate the correlation between the parameters and the histological grades. Sixty-two patients with surgically confirmed HCCs underwent diffusion-weighted magnetic resonance imaging with twelve b values. The differences in the ADC and D values among the groups with G1, G2, and G3 histological grades of the HCCs were statistically significant (P < 0.001). The D* and f values had no significant differences among the different histological grades of the HCCs (P > 0.05). A significant correlation was obtained between the ADC, D, and D* values and the histological grades (P < 0.05). The ROC analyses demonstrated that the D and ADC values had better diagnostic performances in differentiating low-grade HCCs from high-grade HCCs. These results suggested that the IVIM-DWI parameters might be useful in assessing the differentiation grades of carcinomas, which might be helpful in predicting the patient prognoses. |
| Publish Date |
2018-02-27 05:35 |
| Citation |
Zhu SC, Liu YH, Wei Y, Li LL, Dou SW, Sun TY, Shi DP. Intravoxel incoherent motion diffusion-weighted magnetic resonance imaging for predicting histological grade of hepatocellular carcinoma: Comparison with conventional diffusion-weighted imaging. World J Gastroenterol 2018; 24(8): 929-940 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i8/929.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i8.929 |
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