Publication Name	World Journal of Gastroenterology
Manuscript ID	3741
Country	China

Received	2013-05-19 10:49
Peer-Review Started	2013-05-20 12:30
First Decision by Editorial Office Director
Return for Revision	2013-07-31 09:03
Revised	2013-10-08 22:56
Publication Fee Transferred
Second Decision by Editor	2013-11-04 18:08
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-11-05 11:04
Articles in Press
Edit the Manuscript by Language Editor	2013-11-13 18:11
Typeset the Manuscript	2013-12-06 09:26
Publish the Manuscript Online	2013-12-18 10:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Autobiography
Article Title	Neutrophil-lymphocyte ratio predicts the prognosis of patients with hepatocellular carcinoma after liver transplantation
Manuscript Source	Invited Manuscript
All Author List	Guang-Qin Xiao, Chang Liu, Da-Li Liu, Jia-Yin Yang and Lu-Nan Yan
Funding Agency and Grant Number	Funding Agency Grant Number National Science and Technology Major Project of China 2012ZX10002-016 National Science and Technology Major Project of China 2012ZX10002017-017
Corresponding Author	Lu-Nan Yan, PhD, Department of Liver and Vascular Surgery, West China Hospital of Sichuan University, Wuhou District No. 37, Chengdu 610041, Sichuan Province, China. yanlunan1268@163.com
Key Words	Hepatocellular carcinoma; Liver transplantation; Inflammatory reaction; Neutrophil-lymphocyte ratio; Hepatitis B virus
Core Tip	Inflammation has been linked to the biological characteristics of tumors. The neutrophil-lymphocyte ratio (NLR) is a simple biomarker of inflammation. Several studies have reported that a preoperative elevated NLR (in peripheral blood) is negatively associated with the prognosis of patients with hepatocellular carcinoma (HCC) after liver transplantation (LT). However, the ideal cut-off value is controversial, with studies citing both 3 and 5 as the appropriate cut-off NLR. In this study, we report 326 HCC patients who had undergone LT at our center. We identify NLR = 4 as the cut-off point for predicting the prognosis of HCC patients after LT.
Publish Date	2013-12-18 10:39
Citation	Xiao GQ, Liu C, Liu DL, Yang JY, Yan LN. Neutrophil-lymphocyte ratio predicts prognosis of patients with hepatocellular carcinoma after liver transplantation. World J Gastroenterol 2013; 19(45): 8398-8407
URL	http://www.wjgnet.com/1007-9327/full/v19/i45/8398.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i45.8398

Full Article (PDF)	WJG-19-8398.pdf
Manuscript File	3741-Review.doc
Answering Reviewers	3741-Answering Reviewers.pdf
Copyright License Agreement	3741-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	3741-Language certificate.pdf
Peer-review Report	3741-Peer reviews.pdf
Scientific Editor Work List	3741-Scientific editor work list.doc