Publication Name	World Journal of Rheumatology
Manuscript ID	3750
Country	Türkiye

Received	2013-05-20 08:50
Peer-Review Started	2013-05-20 20:39
To Make the First Decision	2013-07-19 08:54
Return for Revision	2013-07-20 22:51
Revised	2013-07-22 21:37
Second Decision	2013-08-20 12:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-08-20 13:36
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-09-18 18:20
Publish the Manuscript Online	2013-11-19 16:17

ISSN	2220-3214 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Rheumatology
Manuscript Type	Review
Article Title	Juvenile idiopathic arthritis
Manuscript Source	Invited Manuscript
All Author List	Balahan Makay, Erbil Unsal and Ozgur Kasapcopur
Funding Agency and Grant Number
Corresponding Author	Ozgur Kasapcopur, Professor of Pediatrics, Department of Pediatric Rheumatology, Cerrahpasa Medical Faculty, Istanbul University, Paşa Sk, 34098 Istanbul, Turkey. ozgurkc@istanbul.edu.tr
Key Words	Juvenile idiopathic arthritis; Classification; Etiopathogenesis; Treatment; Prognosis; Outcome
Core Tip	Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatologic disease in children. Diagnosis of JIA is based on the history and physical examination findings. There is not a diagnostic laboratory test for JIA. Recent advances in the understanding of the immune system pathways involved in inflammation and self-tolerance have provided new targets for treatment of JIA. Biologic agents targeting key cytokines implicated in JIA, suh as tumor necrosis factor ?, interleukin (IL)-1, and IL-6 as well as signaling molecules involved in the regulation of B-cell and T-cell lymphocyte responses, have promising results.
Publish Date	2013-11-19 16:17
Citation	Makay B, Unsal E, Kasapcopur O. Juvenile idiopathic arthritis.World J Rheumatol 2013; 3(3): 16-24
URL	http://www.wjgnet.com/2220-3214/full/v3/i3/16.htm
DOI	http://dx.doi.org/10.5499/wjr.v3.i3.16

Full Article (PDF)	WJR-3-16.pdf
Manuscript File	3750-Review.doc
Answering Reviewers	3750-Answering reviewers.pdf
Copyright License Agreement	3750-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	3750-Language certificate.pdf
Peer-review Report	3750-Peer review(s).pdf
Scientific Editor Work List	3750-Scientific editor work list.doc