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Articles Published Processes
3/5/2018 11:23:39 AM | Browse: 1247 | Download: 1888
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Received |
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2018-01-10 15:39 |
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Peer-Review Started |
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2018-01-10 18:41 |
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To Make the First Decision |
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2018-01-17 01:32 |
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Return for Revision |
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2018-01-18 06:02 |
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Revised |
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2018-02-05 14:24 |
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Second Decision |
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2018-02-08 05:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-02-09 05:35 |
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Articles in Press |
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2018-02-09 05:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-03-03 07:06 |
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Publish the Manuscript Online |
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2018-03-05 11:23 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Can bacterial virulence factors predict antibiotic resistant Helicobacter pylori infection?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Denise E Brennan, Colin Dowd, Colm O'Morain, Deirdre McNamara and Sinead M Smith |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Health Research Board |
HRA-POR-2014-526 |
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| Corresponding Author |
Sinead M Smith, PhD, Assistant Professor, Department of Clinical Medicine, Trinity College Dublin, Trinity Centre
Tallaght Hospital, Dublin D24, Ireland. smithsi@tcd.ie |
| Key Words |
Helicobacter pylori; Antibiotic resistance; Fluoroquinolone; Clarithromycin; Virulence factor; VacA; CagA |
| Core Tip |
The management of Helicobacter pylori (H. pylori) infection is challenging, largely due to the emergence of antibiotic resistance. A greater understanding of local antibiotic resistance rates is important in determining the most appropriate treatment regimen in a given population. Furthermore, insight into the virulence of the infecting strains and the association between virulence and antibiotic resistance could potentially be an avenue to explore in the effort to improve eradication rates. This study provides and update on the prevalence of clarithromycin and fluoroquinolone resistance in Ireland and demonstrates that less virulent strains of H. pylori are predictive of primary clarithromycin resistance. |
| Publish Date |
2018-03-05 11:23 |
| Citation |
Brennan DE, Dowd C, O’Morain C, McNamara D, Smith SM. Can bacterial virulence factors predict antibiotic resistant Helicobacter pylori infection? World J Gastroenterol 2018; 24(9): 971-981 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i9/971.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i9.971 |
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