Publication Name	World Journal of Stem Cells
Manuscript ID	37613
Country	United States

Received	2017-12-22 22:22
Peer-Review Started	2017-12-23 14:27
To Make the First Decision	2018-01-05 01:25
Return for Revision	2018-01-06 06:32
Revised	2018-03-06 08:14
Second Decision	2018-03-06 09:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-03-06 17:31
Articles in Press	2018-03-06 17:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-03-07 01:52
Publish the Manuscript Online	2018-03-07 08:05

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell Biology
Manuscript Type	Minireviews
Article Title	Spatiotemporal switching signals for cancer stem cell activation in pediatric origins of adulthood cancer: Towards a watch-and-wait lifetime strategy for cancer treatment
Manuscript Source	Invited Manuscript
All Author List	Shengwen Calvin Li and Mustafa H Kabeer
ORCID	Author(s) ORCID Number Shengwen Calvin Li http://orcid.org/0000-0002-9699-9204
Funding Agency and Grant Number
Corresponding Author	Shengwen Calvin Li, PhD, Professor, Neuro-oncology and Stem Cell Research Laboratory, Children's Hospital of Orange County, Department of Neurology, University of California-Irvine School of Medicine, 455 South Main Street, Orange, CA 92868-3874, United States. shengwel@uci.edu
Key Words	Pediatric origins of adult cancer; Imaging of single cells
Core Tip	How does ‘spatiotemporal tracking of cancer stem cells’ should be achieved in an organism for pediatric origins of adult cancer? Improving the resolution of current imaging technologies down to the single cell level is essential; however, how single cells could be tracked label-free throughout the lifetime of a human body will be challenging. Such technologies, if developed, can potentially provide an evidence base for cancer prevention and treatment.
Publish Date	2018-03-07 08:05
Citation	Li SC, Kabeer MH. Spatiotemporal switching signals for cancer stem cell activation in pediatric origins of adulthood cancer: Towards a watch-and-wait lifetime strategy for cancer treatment. World J Stem Cells 2018; 10(2): 15-22
URL	http://www.wjgnet.com/1948-0210/full/v10/i2/15.htm
DOI	http://dx.doi.org/10.4252/wjsc.v10.i2.15

Full Article (PDF)	WJSC-10-15.pdf
Full Article (Word)	WJSC-10-15.doc
Manuscript File	37613-Review.docx
Answering Reviewers	37613-Answering reviewers.pdf
Audio Core Tip	37613-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	37613-Conflict-of-interest statement.pdf
Copyright License Agreement	37613-Copyright assignment.pdf
Peer-review Report	37613-Peer-review(s).pdf
Scientific Misconduct Check	37613-Scientific misconduct check.pdf
Scientific Editor Work List	37613-Scientific editor work list.pdf