Publication Name	World Journal of Otorhinolaryngology
Manuscript ID	3775
Country	Australia

Received	2013-05-22 09:15
Peer-Review Started	2013-05-22 20:06
To Make the First Decision	2013-06-24 10:27
Return for Revision	2013-07-01 13:34
Revised
Second Decision	2013-07-19 07:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-07-19 11:48
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-27 06:54
Publish the Manuscript Online	2013-09-06 21:03

ISSN	2218-6247 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Otorhinolaryngology
Manuscript Type	Review
Article Title	Noise-induced hearing loss in the 21st century: A research and translational update
Manuscript Source	Invited Manuscript
All Author List	Ann Chi Yan Wong, Kristina E Froud and Yves Shang-Yi Hsieh
Funding Agency and Grant Number
Corresponding Author	Ann Chi Yan Wong, PhD, Translational Neuroscience Facility, Department of Physiology, Faculty of Medicine, School of Medical Sciences, University of New South Wales, UNSW, Sydney NSW 2052, Australia. acy.wong@unsw.edu.au
Key Words	Noise-induced hearing loss; Otoprotective strategies; Genetic susceptibility; Cochlea; Antioxidants
Core Tip	Noise-induced hearing loss (NIHL) affects millions of people worldwide irrespective of age, sex, and race. Hearing aids and cochlear implants are currently the only available interventions. This review article summarizes the cellular and molecular mechanisms of NIHL to-date. Significant milestones in uncovering genetic predisposition to NIHL in humans, experimental gene therapies and post-noise otoprotective strategies to reduce the impact of NIHL are reviewed.
Publish Date	2013-09-06 21:03
Citation	Wong ACY, Froud KE, Hsieh YSY. Noise-induced hearing loss in the 21st century: A research and translational update. World J Otorhinolaryngol 2013; 3(3): 58-70
URL	http://www.wjgnet.com/2218-6247/full/v3/i3/58.htm
DOI	http://dx.doi.org/10.5319/wjo.v3.i3.58

Full Article (PDF)	WJO-3-58.pdf
Manuscript File	3775-Review.docx
Answering Reviewers	3775-Answering reviewers.pdf
Copyright License Agreement	3775-Copyright assignment.pdf
Peer-review Report	3775-Peer review(s).pdf
Scientific Editor Work List	3775-Scientific editor work list.doc