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5/16/2018 7:38:21 AM | Browse: 283 | Download: 177
Publication Name World Journal of Clinical Cases
Manuscript ID 37831
Country of Manuscript Source China
Received
2018-01-13 05:06
Peer-Review Started
2018-01-13 08:36
To Make the First Decision
2018-02-11 03:41
Return for Revision
2018-02-27 09:44
Revised
2018-03-04 17:11
Second Decision
2018-03-14 09:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-03-20 03:25
Articles in Press
2018-03-20 03:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-04-11 15:48
Publish the Manuscript Online
2018-05-16 07:38
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author (s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Medicine, Research and Experimental
Manuscript Type Retrospective Cohort Study
Article Title Effect and safety of sorafenib in patients with intermediate hepatocellular carcinoma who received transarterial chemoembolization: A retrospective comparative study
Manuscript Source Invited Manuscript
All Author List Xue-Fen Lei, Yang Ke, Tian-Hao Bao, Hao-Ran Tang, Xue-Song Wu, Zhi-Tian Shi, Jie Lin, Zhi-Xian Zhang, Hou Gu and Lin Wang
ORCID
Author(s) ORCID Number
Xue-Fen Lei http://orcid.org/0000-0002-1775-6619
Yang Ke http://orcid.org/0000-0001-6560-5180
Tian-Hao Bao http://orcid.org/0000-0002-9072-3725
Hao-Ran Tang http://orcid.org/0000-0002-6039-9776
Xue-Song Wu http://orcid.org/0000-0002-2412-5436
Zhi-Tian Shi http://orcid.org/0000-0003-4393-886X
Jie Lin http://orcid.org/0000-0003-0213-4275
Zhi-Xian Zhang http://orcid.org/0000-0001-7701-2673
Hou Gu http://orcid.org/0000-0003-4092-4091
Lin Wang http://orcid.org/0000-0001-7383-934x
Funding Agency and Grant Number
Funding Agency Grant Number
Medical Leading Talent Project of Yunnan Province L201622
Corresponding author Lin Wang, PhD, Professor, Surgical Oncologist, Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Kunming Medical University, 1168 Chunrongxi Rd, Kunming 650500, Yunnan Province, China. wanglin@acgxg.com
Keywords Sorafenib; Hepatocellular carcinoma; Transarterial chemoembolization; Overall survival; Adverse reaction
Core Tip Hepatocellular carcinoma (HCC) is a common digestive tract malignancy. Transarterial chemoembolization (TACE) is the standard treatment for intermediate-stage HCC, and it has a limited beneficial effect. To evaluate the safety and efficacy of sorafenib plus TACE treatment for intermediate-stage HCC. Sixty-seven patients with intermediate-stage HCC who were treated with sorafenib plus TACE or TACE alone between 2009 and 2011 were included in the study. This study confirms that sorafenib plus TACE treatment for intermediate-stage HCC significantly prolonged the median overall survival of patients compared to TACE treatment alone. Moreover, this new treatment approach showed tolerable toxicity.
Publish Date 2018-05-16 07:38
Citation Lei XF, Ke Y, Bao TH, Tang HR, Wu XS, Shi ZT, Lin J, Zhang ZX, Gu H, Wang L. Effect and safety of sorafenib in patients with intermediate hepatocellular carcinoma who received transarterial chemoembolization: A retrospective comparative study. World J Clin Cases 2018; 6(5): 74-83
Url http://www.wjgnet.com/2307-8960/full/v6/i5/74.htm
DOI http://dx.doi.org/10.12998/wjcc.v6.i5.74
Full Article (PDF) WJCC-6-74.pdf
Full Article (Word) WJCC-6-74.doc
Manuscript File 37831-Review.doc
Answering Reviewers 37831-Answering reviewers.pdf
Audio Core Tip 37831-Audio core tip.mp3
Biostatistics Review Certificate 37831-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 37831-Conflict-of-interest statement.pdf
Copyright License Agreement 37831-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 37831-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 37831-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 37831-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 37831-Language certificate.pdf
Supplementary Material 37831-Supplementary-Material-revision.pdf
Peer-review Report 37831-Peer-review(s).pdf
Scientific Misconduct Check 37831-Scientific misconduct check.pdf
Scientific Editor Work List 37831-Scientific editor work list.pdf