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Articles Published Processes
4/4/2018 1:15:45 PM | Browse: 1109 | Download: 1974
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Received |
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2018-01-10 04:41 |
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Peer-Review Started |
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2018-01-10 19:14 |
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To Make the First Decision |
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2018-02-05 01:17 |
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Return for Revision |
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2018-02-09 01:12 |
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Revised |
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2018-03-05 00:00 |
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Second Decision |
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2018-03-06 09:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-03-06 16:57 |
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Articles in Press |
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2018-03-06 16:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-03-16 21:29 |
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Typeset the Manuscript |
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2018-04-03 05:47 |
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Publish the Manuscript Online |
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2018-04-04 13:15 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Fecal microbial dysbiosis in Chinese patients with inflammatory bowel disease
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Hai-Qin Ma, Ting-Ting Yu, Xiao-Jing Zhao, Yi Zhang and Hong-Jie Zhang |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81470827 |
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Corresponding Author |
Hong-Jie Zhang, PhD, Professor, Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China. hjzhang06@163.com |
Key Words |
Crohn’s disease; Ulcerative colitis; Chinese; Microbial dysbiosis; 16S ribosomal DNA |
Core Tip |
Intestinal microbiota plays an important role in the pathogenesis of inflammatory bowel disease. However, there are few data on global alteration of microbiota in Chinese patients. In this study, fecal samples were subjected to 16S ribosomal DNA sequencing. Community richness and microbial structure in inflammatory bowel disease were significantly different from those in normal controls. The relative abundance of Bacteroidetes in the active Crohn’s disease group was significantly lower than that in the inactive Crohn’s disease group, and it showed a negative correlation with Crohn’s disease activity index, which indicates that Bacteroidetes may have a negative impact on inflammatory development. |
Publish Date |
2018-04-04 13:15 |
Citation |
Ma HQ, Yu TT, Zhao XJ, Zhang Y, Zhang HJ. Fecal microbial dysbiosis in Chinese patients with inflammatory bowel disease. World J Gastroenterol 2018; 24(13): 1464-1477 |
URL |
http://www.wjgnet.com/1007-9327/full/v24/i13/1464.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v24.i13.1464 |
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