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4/4/2018 1:15:45 PM | Browse: 959 | Download: 1318
Publication Name World Journal of Gastroenterology
Manuscript ID 37881
Country/Territory China
Received
2018-01-10 04:41
Peer-Review Started
2018-01-10 19:14
To Make the First Decision
2018-02-05 01:17
Return for Revision
2018-02-09 01:12
Revised
2018-03-05 00:00
Second Decision
2018-03-06 09:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-03-06 16:57
Articles in Press
2018-03-06 16:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-03-16 21:29
Typeset the Manuscript
2018-04-03 05:47
Publish the Manuscript Online
2018-04-04 13:15
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Fecal microbial dysbiosis in Chinese patients with infla­mmatory bowel disease
Manuscript Source Unsolicited Manuscript
All Author List Hai-Qin Ma, Ting-Ting Yu, Xiao-Jing Zhao, Yi Zhang and Hong-Jie Zhang
ORCID
Author(s) ORCID Number
Hai-Qin Ma http://orcid.org/0000-0002-2900-5994
Ting-Ting Yu http://orcid.org/0000-0003-3433-9013
Xiao-Jing Zhao http://orcid.org/0000-0001-5156-3864
Yi Zhang http://orcid.org/0000-0002-3072-6043
Hong-Jie Zhang http://orcid.org/0000-0003-4497-0503
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81470827
Corresponding Author Hong-Jie Zhang, PhD, Professor, Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China. hjzhang06@163.com
Key Words Crohn’s disease; Ulcerative colitis; Chinese; Microbial dysbiosis; 16S ribosomal DNA
Core Tip Intestinal microbiota plays an important role in the pathogenesis of inflammatory bowel disease. However, there are few data on global alteration of microbiota in Chinese patients. In this study, fecal samples were subjected to 16S ribosomal DNA se­quencing. Community richness and microbial structure in inflammatory bowel disease were significantly different from those in normal controls. The relative abundance of Bacteroidetes in the active Crohn’s disease group was significantly lower than that in the inactive Crohn’s disease group, and it showed a negative correlation with Crohn’s disease activity index, which indicates that Bacteroidetes may have a negative impact on inflammatory development.
Publish Date 2018-04-04 13:15
Citation Ma HQ, Yu TT, Zhao XJ, Zhang Y, Zhang HJ. Fecal microbial dysbiosis in Chinese patients with inflammatory bowel disease. World J Gastroenterol 2018; 24(13): 1464-1477
URL http://www.wjgnet.com/1007-9327/full/v24/i13/1464.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i13.1464
Full Article (PDF) WJG-24-1464.pdf
Full Article (Word) WJG-24-1464.doc
Manuscript File 37881-Review.docx
Answering Reviewers 37881-Answering reviewers.pdf
Audio Core Tip 37881-Audio core tip.MP3
Biostatistics Review Certificate 37881-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 37881-Conflict-of-interest statement.pdf
Copyright License Agreement 37881-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 37881-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 37881-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 37881-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 37881-Language certificate.pdf
Supplementary Material 37881-Supplementary material.pdf
Peer-review Report 37881-Peer-review(s).pdf
Scientific Misconduct Check 37881-Scientific misconduct check.pdf
Scientific Editor Work List 37881-Scientific editor work list.pdf