Publication Name	World Journal of Gastroenterology
Manuscript ID	3796
Country	Czech Republic

Received	2013-05-24 09:41
Peer-Review Started	2013-05-24 14:56
First Decision by Editorial Office Director
Return for Revision	2013-07-01 13:38
Revised	2013-07-25 17:57
Publication Fee Transferred
Second Decision by Editor	2013-08-16 19:49
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-08-17 00:34
Articles in Press
Edit the Manuscript by Language Editor	2014-04-06 23:19
Typeset the Manuscript	2014-05-04 14:32
Publish the Manuscript Online	2014-05-18 12:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Genetics & Heredity
Manuscript Type	Autobiography
Article Title	ABCB4 mutations underlie hormonal cholestasis but not pediatric idiopathic gallstones
Manuscript Source	Invited Manuscript
All Author List	Milan Jirsa, Jiří Bronský, Lenka Dvořáková, Jan Šperl, Vít Šmajstrla, Jiří Horák, Jiří Nevoral and Martin Hřebíček
Funding Agency and Grant Number	Funding Agency Grant Number IKEM, Prague, Czech Republic 00023001 PRVOUK-P24/LF1/3 to Dvořáková L and Hřebíček M MH CZ - DRO VFN64165 to Dvořáková L and Hřebíček M
Corresponding Author	Milan Jirsa, MD, PhD, Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Vídeňská 1958/9, 14021 Prague, Czech Republic. milan.jirsa@ikem.cz
Key Words	Idiopathic cholelithiasis; Intrahepatic cholestasis; Oral contraceptives; Low phospholipid-associated cholelithiasis; Gallbladder disease 1
Core Tip	Mutations in ABCB4 are not overrepresented in children with idiopathic gallstones who fulfill the clinical and laboratory criteria for low phospholipid-associated cholelithiasis syndrome (Gallbladder Disease 1, OMIM #600803). Sexual immaturity prevents manifestation of low phospholipid-associated cholelithiasis. In young females, manifestation of low phospholipid-associated cholelithiasis syndrome such as intrahepatic cholestasis with elevated serum activity of gamma-glutamyltransferase may be induced by hormonal contraceptives.
Publish Date	2014-05-18 12:31
Citation	Jirsa M, Bronský J, Dvořáková L, Šperl J, Šmajstrla V, Horák J, Nevoral J, Hřebíček M. ABCB4 mutations underlie hormonal cholestasis but not pediatric idiopathic gallstones. World J Gastroenterol 2014; 20(19): 5867-5874
URL	http://www.wjgnet.com/1007-9327/full/v20/i19/5867.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i19.5867

Full Article (PDF)	WJG-20-5867.pdf
Full Article (Word)	WJG-20-5867.doc
Manuscript File	3796-Review.docx
Answering Reviewers	3796-Answering reviewers.pdf
Copyright License Agreement	3796-Copyright assignment.doc
Non-Native Speakers of English Editing Certificate	3796-Language certificate.docx
Peer-review Report	3796-Peer review(s).pdf
Scientific Editor Work List	3796-Scientific editor work list.doc