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Articles Published Processes
4/4/2018 1:15:45 PM | Browse: 1047 | Download: 2038
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Received |
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2018-01-31 09:07 |
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Peer-Review Started |
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2018-01-31 18:41 |
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To Make the First Decision |
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2018-02-24 01:42 |
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Return for Revision |
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2018-02-26 03:58 |
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Revised |
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2018-03-03 11:09 |
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Second Decision |
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2018-03-09 07:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-03-10 14:58 |
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Articles in Press |
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2018-03-10 14:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-04-03 05:46 |
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Publish the Manuscript Online |
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2018-04-04 13:15 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis
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Manuscript Source |
Invited Manuscript |
All Author List |
takefumi kimura, naoki tanaka, naoyuki fujimori, ayumi sugiura, tomoo yamazaki, satoru joshita, michiharu komatsu, takeji umemura, akihiro matsumoto and eiji tanaka |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
naoki tanaka, MD, PhD, Associate Professor, Doctor, Doctor, Department of Metabolic Regulation, Shinshu University Graduate School of Medicine and Research Center for Agricultural Food Industry, Shinshu University, 3-1-1 Asahi, Matsumoto 3908621, Nagano, Japan. naopi@shinshu-u.ac.jp |
Key Words |
Non-alcoholic fatty liver disease; Ethanol; Hepatocellular carcinoma; Risk factor |
Core Tip |
This study focused on the impact of a mild drinking habit on liver carcinogenesis in 301 biopsy-proven non-alcoholic fatty liver disease (NAFLD) patients. Multivariate analysis revealed that mild drinking of < 20 g/d might increase the risk of hepatocellular carcinoma in NAFLD patients, particularly those with advanced fibrosis (F3-4). NAFLD patients with severe fibrosis should abstain from even small amounts of regular alcohol consumption. |
Publish Date |
2018-04-04 13:15 |
Citation |
Kimura T, Tanaka N, Fujimori N, Sugiura A, Yamazaki T, Joshita S, Komatsu M, Umemura T, Matsumoto A, Tanaka E. Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis. World J Gastroenterol 2018; 24(13): 1440-1450 |
URL |
http://www.wjgnet.com/1007-9327/full/v24/i13/1440.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v24.i13.1440 |
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