Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	3821
Country	Germany

Received	2013-05-26 07:25
Peer-Review Started	2013-05-26 18:53
To Make the First Decision	2013-07-26 18:37
Return for Revision	2013-07-29 19:47
Revised	2013-08-01 17:31
Second Decision	2013-09-18 10:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-18 11:37
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-21 15:46
Publish the Manuscript Online	2013-11-15 10:10

ISSN	2150-5330 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Review
Article Title	Pancreatic cancer diagnosis by free and exosomal miRNA
Manuscript Source	Invited Manuscript
All Author List	Margot Zöller
Funding Agency and Grant Number
Corresponding Author	Dr. Margot Zöller, Department of Tumor Cell Biology, University Hospital of Surgery, Im Neuenheimer Feld 365, D 69120 Heidelberg, Germany. margot.zoeller@uni-heidelberg.de
Key Words	Pancreatic cancer; Exosomes; MicroRNA; Diagnosis; Serum
Core Tip	Patients with pancreatic adenocarcinoma have a dismal prognosis due to late diagnosis prohibiting surgical intervention, which is further burdened by chemo- and radiation resistance. Hope is raised on a minimally invasive diagnosis that is still missing. Recently two diagnostic options are discussed, serum microRNA (miRNA) and serum exosomes. Serum miRNA can be free or vesicle-, particularly, exosomes-enclosed. This review presents an overview on the current state on miRNA as a cancer diagnostics and discusses arguments in favor of tumor exosomes as a diagnostic tool that additionally could provide a powerful therapeutic option in the near future.
Publish Date	2013-11-15 10:10
Citation	Z?ller M. Pancreatic cancer diagnosis by free and exosomal miRNA. World J Gastrointest Pathophysiol 2013; 4(4): 74-90
URL	http://www.wjgnet.com/2150-5330/full/v4/i4/74.htm
DOI	http://dx.doi.org/10.4291/wjgp.v4.i4.74

Full Article (PDF)	WJGP-4-74.pdf
Manuscript File	3821-Review.doc
Answering Reviewers	3821-Answering reviewers.pdf
Copyright License Agreement	3821-Copyright assignment.pdf
Peer-review Report	3821-Peer review(s).pdf
Scientific Editor Work List	3821-Scientific editor work list.doc