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Articles Published Processes
5/7/2018 4:12:16 AM | Browse: 1106 | Download: 1144
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Received |
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2018-02-02 22:47 |
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Peer-Review Started |
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2018-02-05 01:45 |
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To Make the First Decision |
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2018-03-02 00:26 |
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Return for Revision |
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2018-03-07 08:08 |
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Revised |
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2018-03-12 17:45 |
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Second Decision |
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2018-04-19 00:14 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-04-22 17:43 |
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Articles in Press |
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2018-04-22 17:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-04-29 04:49 |
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Publish the Manuscript Online |
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2018-05-07 04:12 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Review |
| Article Title |
Antineutrophil cytoplasmic antibody associated vasculitides with renal involvement: Open challenges in the remission induction therapy
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Maurizio Salvadori and Aris Tsalouchos |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Maurizio Salvadori, MD, Professor, Department of Nephrology and Renal Transplantation, Careggi University Hospital, viale Pieraccini 18, Florence 50139, Italy. maurizio.salvadori1@gmail.com |
| Key Words |
Rapidly progressive glomerulonephritis; Remission induction therapy; Antineutrophil cytoplasmic antibody associated vasculitides; Cyclophosphamide; Rituximab; Corticosteroids; Plasma exchange; Avacopan |
| Core Tip |
Antineutrophil cytoplasmic antibody (ANCA) associated vasculitides with renal involvement, presents as Rapidly Progressive Glomerulonephritis, are organ-threatening and potentially life-threatening diseases. Although remission induction immunosuppressive regimens overall have been very successful in the treatment of these conditions, many questions remain unanswered. The still open challenges and questions concern: (1) The choice of the first-line therapy (cyclophosphamide versus rituximab) based on renal function at baseline, new versus relapsed disease, ANCA specificity, tissue injury and safety; (2) the role of plasma exchange in combination with steroid and non steroid agents and (3) the advent of novel target therapies and strategies. |
| Publish Date |
2018-05-07 04:12 |
| Citation |
Salvadori M, Tsalouchos A. Antineutrophil cytoplasmic antibody associated vasculitides with renal involvement: Open challenges in the remission induction therapy. World J Nephrol 2018; 7(3): 71-83 |
| URL |
http://www.wjgnet.com/2220-6124/full/v7/i3/71.htm |
| DOI |
http://dx.doi.org/10.5527/wjn.v7.i3.71 |
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