Publication Name	World Journal of Gastroenterology
Manuscript ID	3845
Country	Switzerland

Received	2013-05-28 09:44
Peer-Review Started	2013-05-29 15:47
To Make the First Decision	2013-06-24 10:20
Return for Revision	2013-07-01 13:43
Revised	2013-07-30 23:29
Second Decision	2013-09-17 09:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-17 10:45
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-04-21 10:49
Publish the Manuscript Online	2014-05-07 10:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Clinical and histopathological correlations of fecal calprotectin release in colorectal carcinoma
Manuscript Source	Invited Manuscript
All Author List	Frank Serge Lehmann, Francesca Trapani, Ida Fueglistaler, Luigi Maria Terracciano, Markus von Flüe, Gieri Cathomas, Andreas Zettl, Pascal Benkert, Daniel Oertli and Christoph Beglinger
Funding Agency and Grant Number	Funding Agency Grant Number Unrestricted research to Dr. Lehmann FS Pfizer AG, Viollier Laboratories AG, Switzerland performed the fecal calprotectin assays
Corresponding Author	Frank Serge Lehmann, MD, Division of Gastroenterology and Hepatology, University Hospital, Petersgraben 4, 4031 Basel, Switzerland. fslehmann@hin.ch
Key Words	Calprotectin; Colorectal cancer; Inflammation; Tumor size; Granulocytes
Core Tip	Colorectal cancer (CRC) patients have a significant increase of fecal calprotectin release. The mechanisms for this observation are unclear. In our study, we examined the calprotectin release before and after operation of 46 CRC patients. This is the first study that assessed the correlation of calprotectin with both tumor as well as histopathological parameters. Our study contains the following new information: (1) the release of calprotectin is exclusively correlated to the T-stage, but to no histopathological parameters; and (2) except the T-stage, all other tumor characteristics assessed by the seventh edition of the tumor node metastasis classification are not correlated.
Publish Date	2014-05-07 10:10
Citation	Lehmann FS, Trapani F, Fueglistaler I, Terracciano LM, von Flüe M, Cathomas G, Zettl A, Benkert P, Oertli D, Beglinger C. Clinical and histopathological correlations of fecal calprotectin release in colorectal carcinoma. World J Gastroenterol 2014; 20(17): 4994-4999
URL	http://www.wjgnet.com/1007-9327/full/v20/i17/4994.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i17.4994

Full Article (PDF)	WJG-20-4994.pdf
Full Article (Word)	WJG-20-4994.doc
Manuscript File	3845-Review.doc
Answering Reviewers	3845-Answering reviewers.pdf
Biostatistics Review Certificate	ex11LehmannAN_Study1.pdf
Copyright License Agreement	3845-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	3845-Language certificate.pdf
Peer-review Report	3845-Peer review(s).pdf
Scientific Editor Work List	3845-Scientific editor work list.doc