| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Post-polypectomy bleeding and thromboembolism risks associated with warfarin vs direct oral anticoagulants
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Naohiro Yanagisawa, Naoyoshi Nagata, Kazuhiro Watanabe, Tatsuhiro Iida, Mariko Hamada, Sakurako Kobayashi, Takuro Shimbo, Junichi Akiyama and Naomi Uemura |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Grant-in-Aid for Research from the National Center for Global Health and Medicine (29-2001) partly |
|
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| Corresponding Author |
Naoyoshi Nagata, MD, PhD, Doctor, Doctor, Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan. nnagata_ncgm@yahoo.co.jp |
| Key Words |
High-risk endoscopic procedures; Novel oral anticoagulants; Endoscopic guideline validation; Post-procedure gastrointestinal bleeding |
| Core Tip |
First, we found that anticoagulant (AC) users were at higher risk of post-polypectomy bleeding (PPB) than controls. Second, PPB risk was similar between warfarin users and direct oral anticoagulant users, whereas thromboembolism risk was observed only in warfarin users. Third, PPB risk was not significantly different between rivaroxaban, dabigatran, and apixaban users. Fourth, the strategy of discontinuing AC with heparin bridge as recommended in the endoscopy guidelines showed a higher bleeding rate than continuing AC alone and had one thrombotic event, thus indicating that heparin bridge increased bleeding and may not prevent thromboembolism. |
| Publish Date |
2018-04-11 08:28 |
| Citation |
Yanagisawa N, Nagata N, Watanabe K, Iida T, Hamada M, Kobayashi S, Shimbo T, Akiyama J, Uemura N. Post-polypectomy bleeding and thromboembolism risks associated with warfarin vs direct oral anticoagulants. World J Gastroenterol 2018; 24(14): 1540-1549 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i14/1540.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i14.1540 |
