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Publication Name World Journal of Gastroenterology
Manuscript ID 3847
Country Spain
Received
2013-05-29 18:39
Peer-Review Started
2013-05-31 15:45
To Make the First Decision
2013-06-24 10:20
Return for Revision
2013-07-01 13:58
Revised
Second Decision
2013-10-21 17:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-10-22 07:11
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2013-10-31 22:05
Typeset the Manuscript
2013-11-23 17:10
Publish the Manuscript Online
2013-12-11 16:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Minireviews
Article Title Splanchnic-aortic inflammatory axis in experimental portal hypertension
Manuscript Source Invited Manuscript
All Author List Maria-Angeles Aller, Natalia de las Heras, Maria-Paz Nava, Javier Regadera, Jaime Arias and Vicente Lahera
Funding Agency and Grant Number
Funding Agency Grant Number
Mutua Madrileña Medical Research Foundation AP5966-2009
Corresponding Author Maria-Angeles Aller, MD, PhD, Surgery Department, School of Medicine, Complutense University of Madrid, Pza. de Ramón y Cajal s.n., 28040 Madrid, Spain. maaller@med.ucm.es
Key Words Portal hypertension; Inflammation; Aortopathy; Hepatic steatosis
Core Tip Triple partial portal vein ligation in the rat induces in the long term (22 mo) both splanchnic alterations, i.e., liver steatosis and portal hypertensive intestinal vasculopathy associated with a portal hypertensive microbiome, and systemic alterations, i.e., a wound-like inflammatory aortic response. These alterations support this experimental model of prehepatic portal hypertension for studying the pathophysiological mechanisms involved in the low-grade inflammatory response produced.
Publish Date 2013-12-11 16:13
Citation Aller MA, de las Heras N, Nava MP, Regadera J, Arias J, Lahera V. Splanchnic-aortic inflammatory axis in experimental portal hypertension. World J Gastroenterol 2013; 19(44): 7992-7999
URL http://www.wjgnet.com/1007-9327/full/v19/i44/7992.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i44.7992
Full Article (PDF) WJG-19-7992.pdf
Manuscript File 3847-Review.doc
Answering Reviewers 3847-Answering reviewers.pdf
Copyright License Agreement 3847-Copyright assignment.pdf
Peer-review Report 3847-Peer review(s).pdf
Scientific Editor Work List 3847-Scientific editor work list.doc