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Articles Published Processes
9/11/2014 8:40:00 PM | Browse: 1304 | Download: 1431
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Received |
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2013-05-29 18:39 |
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Peer-Review Started |
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2013-05-31 15:45 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2013-07-01 13:58 |
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Revised |
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Publication Fee Transferred |
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Second Decision by Editor |
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2013-10-21 17:30 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2013-10-22 07:11 |
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Articles in Press |
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Edit the Manuscript by Language Editor |
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2013-10-31 22:05 |
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Typeset the Manuscript |
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2013-11-23 17:10 |
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Publish the Manuscript Online |
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2013-12-11 16:13 |
| Category |
Surgery |
| Manuscript Type |
Minireviews |
| Article Title |
Splanchnic-aortic inflammatory axis in experimental portal hypertension
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Maria-Angeles Aller, Natalia de las Heras, Maria-Paz Nava, Javier Regadera, Jaime Arias and Vicente Lahera |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Mutua Madrileña Medical Research Foundation |
AP5966-2009 |
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| Corresponding Author |
Maria-Angeles Aller, MD, PhD, Surgery Department, School of Medicine, Complutense University of Madrid, Pza. de Ramón y Cajal s.n., 28040 Madrid, Spain. maaller@med.ucm.es |
| Key Words |
Portal hypertension; Inflammation; Aortopathy; Hepatic steatosis |
| Core Tip |
Triple partial portal vein ligation in the rat induces in the long term (22 mo) both splanchnic alterations, i.e., liver steatosis and portal hypertensive intestinal vasculopathy associated with a portal hypertensive microbiome, and systemic alterations, i.e., a wound-like inflammatory aortic response. These alterations support this experimental model of prehepatic portal hypertension for studying the pathophysiological mechanisms involved in the low-grade inflammatory response produced. |
| Publish Date |
2013-12-11 16:13 |
| Citation |
Aller MA, de las Heras N, Nava MP, Regadera J, Arias J, Lahera V. Splanchnic-aortic inflammatory axis in experimental portal hypertension. World J Gastroenterol 2013; 19(44): 7992-7999 |
| URL |
http://www.wjgnet.com/1007-9327/full/v19/i44/7992.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v19.i44.7992 |
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