Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	38475
Country	Japan

Received	2018-02-23 01:06
Peer-Review Started	2018-02-23 01:31
To Make the First Decision	2018-03-19 00:43
Return for Revision	2018-03-23 02:10
Revised	2018-03-23 06:07
Second Decision	2018-04-18 11:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-04-20 20:19
Articles in Press	2018-04-20 20:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-06-01 04:10
Publish the Manuscript Online	2018-06-15 06:10

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Emerging evidence of the molecular landscape specific for hematogenous metastasis from gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Dai Shimizu, Mitsuro Kanda and Yasuhiro Kodera
ORCID	Author(s) ORCID Number Dai Shimizu http://orcid.org/0000-0001-7982-1079 Mitsuro Kanda http://orcid.org/0000-0001-5464-3819 Yasuhiro Kodera http://orcid.org/0000-0002-6173-7474
Funding Agency and Grant Number
Corresponding Author	Mitsuro Kanda, MD, PhD, Research Fellow, Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. m-kanda@med.nagoya-u.ac.jp
Key Words	Gastric cancer; Hematogenous metastasis; Hepatic metastasis; Molecular mechanism; Biomarker; Premetastatic niche
Core Tip	Gastric cancer (GC) has high cancer-related mortality, which is mainly caused by distant metastasis including hematogenous metastasis. Numerous steps are required to establish a metastatic focus, and understanding the molecular mechanisms of each step is necessary to conquer metastasis. Development and dissemination of sequencing technology have elucidated some of the molecular biological mechanisms associated with cancer metastasis. This review aims to summarize the molecules reportedly contributing to hematogenous metastasis from GC and to become the groundwork for the further development of novel biomarkers and molecular targets.
Publish Date	2018-06-15 06:10
Citation	Shimizu D, Kanda M, Kodera Y. Emerging evidence of the molecular landscape specific for hematogenous metastasis from gastric cancer. World J Gastrointest Oncol 2018; 10(6): 124-136
URL	http://www.wjgnet.com/1948-5204/full/v10/i6/124.htm
DOI	http://dx.doi.org/10.4251/wjgo.v10.i6.124

Full Article (PDF)	WJGO-10-124.pdf
Full Article (Word)	WJGO-10-124.doc
Manuscript File	38475-Review.docx
Answering Reviewers	38475-Answering reviewers.pdf
Audio Core Tip	38475-Audio core tip.wav
Conflict-of-Interest Disclosure Form	38475-Conflict-of-interest statement.pdf
Copyright License Agreement	38475-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	38475-Non-Native-Speakers-of-English-Editing-Certificate-revision.pdf
Peer-review Report	38475-Peer-review(s).pdf
Scientific Editor Work List	38475-Scientific editor work list.pdf