Publication Name	World Journal of Gastroenterology
Manuscript ID	3861
Country	Italy

Received	2013-05-29 08:31
Peer-Review Started	2013-05-29 19:10
To Make the First Decision	2013-06-24 10:19
Return for Revision	2013-07-01 13:59
Revised
Second Decision	2013-09-17 09:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-17 10:45
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-30 12:12
Publish the Manuscript Online	2013-11-13 08:37

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Pathogenesis of hepatic steatosis: The link between hypercortisolism and non-alcoholic fatty liver disease
Manuscript Source	Invited Manuscript
All Author List	Giovanni Tarantino and Carmine Finelli
Funding Agency and Grant Number
Corresponding Author	Giovanni Tarantino, MD, Department of Clinical Medicine and Surgery, Federico Ⅱ University Medical School of Naples, Via Sergio Pansini, 5, 80131 Naples, Italy. tarantin@unina.it
Key Words	Nonalcoholic fatty liver disease; Cushing’s syndrome; Hypercotisolism
Core Tip	This overview of the literature is related to hepatic steatosis, its prevalence, clinical consequences and, in particular, the pathogenesis of this disorder. The authors focus on the link between hypercortisolism and obesity/metabolic syndrome. The main question of the work relates to the low prevalence of hepatic steatosis (only 20%) described in 50 newly diagnosed patients with Cushing’s syndrome based on appropriate computed tomography scans available for retrospective analysis. The authors try to explain this finding by the anti-inflammatory effect of high circulating levels of glucocorticoids.
Publish Date	2013-11-13 08:37
Citation	Tarantino G, Finelli C. Pathogenesis of hepatic steatosis: The link between hypercortisolism and non-alcoholic fatty liver disease. World J Gastroenterol 2013; 19(40): 6735-6743
URL	http://www.wjgnet.com/1007-9327/full/v19/i40/6735.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i40.6735

Full Article (PDF)	WJG-19-6735.pdf
Manuscript File	3861-Review.doc
Answering Reviewers	3861-Answering reviewers.pdf
Copyright License Agreement	3861-Copyright assignment.pdf
Peer-review Report	3861-Peer review(s).pdf
Scientific Editor Work List	3861-Scientific editor work list.doc