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9/14/2018 5:53:04 AM | Browse: 713 | Download: 1630
Publication Name World Journal of Gastroenterology
Manuscript ID 38616
Country Japan
Received
2018-04-04 01:21
Peer-Review Started
2018-04-04 07:37
To Make the First Decision
2018-05-30 00:35
Return for Revision
2018-06-04 06:55
Revised
2018-07-12 13:28
Second Decision
2018-07-20 07:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-07-21 18:02
Articles in Press
2018-07-21 18:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-09-03 08:12
Publish the Manuscript Online
2018-09-14 05:53
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Gastroduodenal ulcer bleeding in elderly patients on low dose aspirin therapy
Manuscript Source Unsolicited Manuscript
All Author List Koh Fukushi, Keiichi Tominaga, Kazunori Nagashima, Akira Kanamori, Naoya Izawa, Mimari Kanazawa, Takako Sasai and Hideyuki Hiraishi
ORCID
Author(s) ORCID Number
Koh Fukushi http://orcid.org/0000-0001-8079-3386
Keiichi Tominaga http://orcid.org/0000-0002-3716-3386
Kazunori Nagashima http://orcid.org/0000-0002-0510-7179
Akira Kanamori http://orcid.org/0000-0001-9698-9957
Naoya Izawa http://orcid.org/orcid.org/0000-0002-2467-9367
Mimari Kanazawa http://orcid.org/0000-0003-2243-4267
Takako Sasai http://orcid.org/0000-0002-0596-7013
Hideyuki Hiraishi http://orcid.org/0000-0002-0721-5018
Funding Agency and Grant Number
Corresponding Author Keiichi Tominaga, MD, PhD, Doctor, Department of Gastroenterology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotuga, Tochigi 3210293, Japan. tominaga@dokkyomed.ac.jp
Key Words Hemorrhagic gastroduodenal ulcer; Low-dose aspirin; Antithrombotic drugs; Elderly patients; Proton pump inhibitor
Core Tip A total of 1105 patients with hemorrhagic gastro¬duodenal ulcer were grouped by age and drugs used, and these groups were compared in several factors. Among the elderly (over 70 years), the rate of severe conditions was significantly higher in patients receiving low-dose aspirin (LDA) combination therapy than in those receiving LDA monotherapy. Meanwhile, in the LDA monotherapy group, no significant difference in the rate of severe conditions was observed between elderly and non-elderly patients. This result suggests LDA combination therapy contributes to the aggravation, and advanced age is not an aggravating factor when LDA monotherapy is used.
Publish Date 2018-09-14 05:53
Citation Fukushi K, Tominaga K, Nagashima K, Kanamori A, Izawa N, Kanazawa M, Sasai T, Hiraishi H. Gastroduodenal ulcer bleeding in elderly patients on low dose aspirin therapy. World J Gastroenterol 2018; 24(34): 3908-3918
URL http://www.wjgnet.com/1007-9327/full/v24/i34/3908.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i34.3908
Full Article (PDF) WJG-24-3908.pdf
Full Article (Word) WJG-24-3908.doc
STROBE Statement 38616-STROBE statement.pdf
Manuscript File 38616-Review.docx
Answering Reviewers 38616-Answering reviewers.pdf
Audio Core Tip 38616-Audio core tip.mp3
Biostatistics Review Certificate 38616-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 38616-Conflict-of-interest statement.pdf
Copyright License Agreement 38616-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 38616-Signed-Informed-Consent-Form(s)-or-Document(s)-revision_0110.pdf
Institutional Review Board Approval Form or Document 38616-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 38616-Language certificate.pdf
Peer-review Report 38616-Peer-review(s).pdf
Scientific Misconduct Check 38616-Scientific misconduct check.pdf
Scientific Editor Work List 38616-Scientific editor work list.pdf