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Articles Published Processes
4/27/2018 12:18:11 AM | Browse: 1088 | Download: 1787
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Received |
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2018-03-06 06:48 |
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Peer-Review Started |
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2018-03-06 07:04 |
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First Decision by Editorial Office Director |
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2018-03-12 21:48 |
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Return for Revision |
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2018-03-13 03:13 |
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Revised |
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2018-03-21 00:03 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2018-04-10 05:57 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2018-04-10 21:57 |
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Articles in Press |
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2018-04-10 21:57 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-04-24 11:48 |
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Publish the Manuscript Online |
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2018-04-27 00:18 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
NF-kB promotes the stem-like properties of leukemia cells by activation of LIN28B
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jianbiao Zhou, Jing-Yuan Chooi, Ying Qing Ching, Jessie Yiying Quah, Sabrina Hui-Min Toh, Yvonne Ng, Tuan Zea Tan and Wee-Joo Chng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Singapore Ministry of Education’s Tier 3 grants |
MOE2014-T3-1-006 |
| the Singapore National Research Foundation and the Ministry of Education under the Research Center of Excellence Program |
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| NMRC Clinician Scientist Investigator award |
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| and NMRC Clinician-Scientist IRG Grant |
CNIG11nov38 |
| the RNA Biology Center at CSI Singapore, NUS |
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| Corresponding Author |
Jianbiao Zhou, MD, PhD, Senior Scientist, Cancer Science Institute of Singapore, National University of Singapore, 28 Medical Drive, Singapore 117456, Singapore. csizjb@nus.edu.sg |
| Key Words |
Nuclear factor kappa B; LIN28B; Leukemia stem cell; Acute myeloid leukemia |
| Core Tip |
In this study, we uncovered that LIN28B is regulated by NF-kB activity on transcriptional level and important for NF-kB-mediated leukemia-stem cell like properties of acute myeloid leukemia cells. NF-kB/LIN28B represents an attractive therapeutic target. |
| Publish Date |
2018-04-27 00:18 |
| Citation |
Zhou J, Chooi JY, Ching YQ, Quah JY, Toh SHM, Ng Y, Tan TZ, Chng WJ. NF-κB promotes the stem-like properties of leukemia cells by activation of LIN28B. World J Stem Cells 2018; 10(4): 34-42 |
| URL |
http://www.wjgnet.com/1948-0210/full/v10/i4/34.htm |
| DOI |
http://dx.doi.org/10.4252/wjsc.v10.i4.34 |
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