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Articles Published Processes
9/15/2014 8:54:00 PM | Browse: 1073 | Download: 987
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Received |
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2013-05-29 08:49 |
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Peer-Review Started |
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2013-05-29 14:50 |
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To Make the First Decision |
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2013-06-09 09:55 |
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Return for Revision |
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2013-06-19 09:29 |
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Revised |
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2013-06-19 21:07 |
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Second Decision |
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2013-07-05 12:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-07-05 13:17 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-07-18 15:54 |
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Publish the Manuscript Online |
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2013-07-29 11:18 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Editorial |
Article Title |
Interplay of autophagy and innate immunity in Crohn's disease: A key immunobiologic feature
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Manuscript Source |
Invited Manuscript |
All Author List |
Györgyi Műzes, Zsolt Tulassay and Ferenc Sipos |
Funding Agency and Grant Number |
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Corresponding Author |
Györgyi Műzes, MD, PhD, Associate Professor of Immunology and Internal Medicine, 2nd Department of Internal Medicine, Semmelweis University, Szentkirályi str. 46, 1088 Budapest, Hungary. muzes.gyorgyi@med.semmelweis-univ.hu |
Key Words |
Crohn's disease; Innate immunity; Autophagy genes; Autophagy; Gut microbiota |
Core Tip |
In case of Crohn's disease, on the basis of autophagy-related risk genetic polymorphisms impaired sensing and responding of intracellular bacteria by innate immunity, closely interrelated with the autophagic and unfolded protein pathways seem to be the most relevant immunobiologic events. Autophagy represents a key regulator mechanism with the capacity to integrate several aspects of Crohn's disease pathogenesis. |
Publish Date |
2013-07-29 11:18 |
Citation |
Műzes G, Tulassay Z, Sipos F. Interplay of autophagy and innate immunity in Crohn’s disease: A key immunobiologic feature. World J Gastroenterol 2013; 19(28): 4447-4454 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i28/4447.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i28.4447 |
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