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5/11/2018 10:51:26 AM | Browse: 957 | Download: 1402
Publication Name World Journal of Gastroenterology
Manuscript ID 38683
Country Norway
Received
2018-03-09 10:09
Peer-Review Started
2018-03-10 02:53
To Make the First Decision
2018-04-11 07:17
Return for Revision
2018-04-13 03:42
Revised
2018-04-20 11:19
Second Decision
2018-04-23 05:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-04-23 16:36
Articles in Press
2018-04-23 16:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-05-10 08:54
Publish the Manuscript Online
2018-05-11 10:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Ischemia/reperfusion injury in porcine intestine - viability assessment
Manuscript Source Unsolicited Manuscript
All Author List Runar James Strand-Amundsen, Henrik Mikael Reims, Finn Reinholt, Tom Erik Ruud, Runkuan Yang, Jan Olav Hogetveit and Tor Inge Tonnessen
ORCID
Author(s) ORCID Number
Runar James Strand-Amundsen http://orcid.org/0000-0002-2224-9355
Henrik Mikael Reims http://orcid.org/0000-0002-2018-7787
Finn Reinholt http://orcid.org/0000-0002-9906-3540
Tom Erik Ruud http://orcid.org/0000-0002-5753-0550
Runkuan Yang http://orcid.org/0000-0001-7401-7057
Jan Olav Hogetveit http://orcid.org/0000-0001-6246-0254
Tor Inge Tonnessen http://orcid.org/0000-0002-3511-5815
Funding Agency and Grant Number
Funding Agency Grant Number
Norwegian Research Council 219819
Corresponding Author Runar James Strand-Amundsen, MSc, Research Scientist, Department of Physics, University of Oslo, Postboks 1048 Blindern, Oslo 0316, Norway. runar.strand-amundsen@fys.uio.no
Key Words Viability; Histology; Microdialysis; Reperfusion; Ischemia; Jejunum; Porcine model
Core Tip Research on experimental methods to improve the surgeon’s assessment of viability of ischemic bowel with higher accuracy than currently possible, requires an accurate reference model. We investigated viability assessment in a porcine model of warm ischemia on jejunum with mesenteric occlusion, followed by reperfusion. Our aim was to determine the time point of irreversible damage, to provide a reference model. We created parallel segmental models on the jejunum in 15 pigs and compared the results from visual inspection with histology and microdialysis. Three hours of ischemia followed by reperfusion appeared to be the upper limit for viability in this model.
Publish Date 2018-05-11 10:51
Citation Strand-Amundsen RJ, Reims HM, Reinholt FP, Ruud TE, Yang R, Høgetveit JO, Tønnessen TI. Ischemia/reperfusion injury in porcine intestine - viability assessment. World J Gastroenterol 2018; 24(18): 2009-2023
URL http://www.wjgnet.com/1007-9327/full/v24/i18/2009.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i18.2009
Full Article (PDF) WJG-24-2009.pdf
Full Article (Word) WJG-24-2009.doc
The ARRIVE Guidelines 38683-The ARRIVE guidelines.pdf
Manuscript File 38683-Review.docx
Answering Reviewers 38683-Answering reviewers.pdf
Audio Core Tip 38683-Audio core tip.mp3
Biostatistics Review Certificate 38683-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 38683-Conflict-of-interest statement.pdf
Copyright License Agreement 38683-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 38683-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 38683-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 38683-Institutional review board statement.pdf
Peer-review Report 38683-Peer-review(s).pdf
Scientific Misconduct Check 38683-Scientific misconduct check.pdf
Scientific Editor Work List 38683-Scientific editor work list.pdf