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Articles Published Processes
7/27/2018 6:43:44 AM | Browse: 1272 | Download: 2203
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Received |
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2018-03-17 07:52 |
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Peer-Review Started |
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2018-03-17 13:35 |
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First Decision by Editorial Office Director |
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2018-04-18 14:31 |
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Return for Revision |
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2018-04-24 07:29 |
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Revised |
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2018-05-09 13:50 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2018-06-21 08:52 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2018-06-21 17:54 |
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Articles in Press |
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2018-06-21 17:54 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-07-25 03:15 |
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Publish the Manuscript Online |
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2018-07-27 06:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Multikinase inhibitor-associated hand-foot skin reaction as a predictor of outcomes in patients with hepatocellular carcinoma treated with sorafenib
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Masanori Ochi, Toshiro Kamoshida, Atsushi Ohkawara, Haruka Ohkawara, Nobushige Kakinoki, Shinji Hirai and Akinori Yanaka |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Masanori Ochi, MD, Doctor, Doctor, Department of Gastroenterology, Hitachi General Hospital, 2-1-1, Jonancho, Hitachi 317-0077, Japan. maochi-tei@umin.ac.jp |
| Key Words |
Hepatocellular carcinoma; Surrogate marker; Multikinase inhibitor-associated hand-foot skin reaction; Sorafenib; Intervention by pharmacists |
| Core Tip |
Sorafenib is an oral anticancer drug associated with a high incidence of adverse reactions. However, no studies have evaluated its therapeutic efficacy under improved adherence. A surrogate marker of significant improvement in overall survival under improved adherence in advanced hepatocellular carcinoma patients after the introduction of sorafenib was multikinase inhibitor-associated hand-foot skin reaction. Intervention by healthcare providers, including pharmacists specializing in cancer treatment, has improved patient adherence, contributing to the true response to sorafenib treatment. |
| Publish Date |
2018-07-27 06:43 |
| Citation |
Ochi M, Kamoshida T, Ohkawara A, Ohkawara H, Kakinoki N, Hirai S, Yanaka A. Multikinase inhibitor-associated hand-foot skin reaction as a predictor of outcomes in patients with hepatocellular carcinoma treated with sorafenib. World J Gastroenterol 2018; 24(28): 3155-3162 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i28/3155.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i28.3155 |
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