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Articles Published Processes
9/27/2018 9:38:46 AM | Browse: 914 | Download: 1228
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Received |
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2018-03-20 02:55 |
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Peer-Review Started |
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2018-03-20 07:25 |
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To Make the First Decision |
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2018-04-13 03:19 |
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Return for Revision |
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2018-04-18 11:11 |
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Revised |
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2018-07-10 10:00 |
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Second Decision |
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2018-07-13 08:55 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-07-16 05:28 |
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Articles in Press |
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2018-07-16 05:28 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-07-27 01:55 |
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Typeset the Manuscript |
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2018-09-20 01:42 |
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Publish the Manuscript Online |
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2018-09-27 09:38 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Progression and status of antiviral monitoring in patients with chronic hepatitis B: From HBsAg to HBV RNA
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ya-Yun Liu and Xue-Song Liang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xue-Song Liang, MD, PhD, Associate Professor, Department of Infectious Diseases, Changhai Hospital of Second Military Medical University, Changhai Road 168#, Shanghai 200433, China. liangxuesong2000@163.com |
| Key Words |
Hepatitis B core-related antigen; Response prediction; Chronic hepatitis B; Interferon; Nucleos(t)ide analogs; Hepatitis B surface antigen; Progenome RNA |
| Core Tip |
As the surrogate biomarkers of intrahepatic viral replicative activity, hepatitis B surface antigen (HBsAg), hepatitis B core-related antigen (HbcrAg), and serum hepatitis B virus (HBV) RNA levels have been advocated as novel serum markers for treatment response in chronic hepatitis B. Currently, quantitative HBsAg has been widely used for predicting treatment response of chronic hepatitis B. HBcrAg can predict the risk of post-treatment reactivation of HBV as it is detectable in patients whose HBV DNA levels are undetectable or HBsAg loss is achieved. Serum HBV RNA may be useful in monitoring drug withdrawal, but clinical studies with large sample sizes remain necessary to further determine this capability. |
| Publish Date |
2018-09-27 09:38 |
| Citation |
Liu YY, Liang XS. Progression and status of antiviral monitoring in patients with chronic hepatitis B: From HBsAg to HBV RNA. World J Hepatol 2018; 10(9): 603-611 |
| URL |
http://www.wjgnet.com/1948-5182/full/v10/i9/603.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v10.i9.603 |
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