Publication Name	World Journal of Nephrology
Manuscript ID	3882
Country	India

Received	2013-05-30 08:10
Peer-Review Started	2013-05-30 09:42
To Make the First Decision	2013-06-24 10:24
Return for Revision	2013-07-04 14:43
Revised
Second Decision	2014-03-04 09:52
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-04 10:16
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-13 17:31
Typeset the Manuscript	2014-05-08 20:22
Publish the Manuscript Online	2014-05-19 21:10

ISSN	2220-6124 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Minireviews
Article Title	Pediatric lupus nephritis: Management update
Manuscript Source	Invited Manuscript
All Author List	Rajiv Sinha and Sumantra Raut
Funding Agency and Grant Number
Corresponding Author	Dr. Rajiv Sinha, PhD, Division of Pediatric Nephrology, Department of Pediatrics, Institute of Child Health, 11 Biresh Guha Street, Kolkata 700017, India. rajivsinha_in@yahoo.com
Key Words	Pediatric; Lupus nephritis; Management; Monoclonal antibody; Cyclophosphamide; Mycophenolate mofetil
Core Tip	Childhood-onset systemic lupus erythematosus (cSLE) is a rare but severe autoimmune disease with multisystem involvement. Renal disease occurs in 50% to 75% of all cSLE patients and is a major cause of increased morbidity and mortality. Originally SLE nephritis was treated with steroids with a poor outcome which improved markedly with the introduction of cyclophosphamide, but at the cost of increased side effects which resulted in a further search for a less toxic, but equally effective regime. Here we discuss some newer drugs including immune-modulators and monoclonal antibodies in addition to azathioprine and mycophenolate mofetil, however, most of the evidence on these medications is restricted to adult literature and pediatric data are extrapolated from these trials.
Publish Date	2014-05-19 21:10
Citation	Sinha R, Raut S. Pediatric lupus nephritis: Management update.World J Nephrol 2014; 3(2): 16-23
URL	http://www.wjgnet.com/2220-6124/full/v3/i2/16.htm
DOI	http://dx.doi.org/10.5527/wjn.v3.i2.16

Full Article (PDF)	WJN-3-16.pdf
Full Article (Word)	WJN-3-16.doc
Manuscript File	3882-Review.doc
Answering Reviewers	3882-Answering reviewers.pdf
Copyright License Agreement	3882-Copyright assignment.pdf
Peer-review Report	3882-Peer reviews.pdf
Scientific Editor Work List	3882-Scientific editor work list.doc