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7/5/2018 1:33:43 AM | Browse: 1035 | Download: 1161
Publication Name World Journal of Gastroenterology
Manuscript ID 38908
Country China
Received
2018-03-22 05:22
Peer-Review Started
2018-03-22 05:24
To Make the First Decision
2018-04-03 00:57
Return for Revision
2018-04-10 11:59
Revised
2018-04-14 13:13
Second Decision
2018-06-01 09:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-06-01 18:31
Articles in Press
2018-06-01 18:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-06-09 19:34
Typeset the Manuscript
2018-07-03 03:46
Publish the Manuscript Online
2018-07-05 01:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Observational Study
Article Title Transforming growth factor-β and peripheral regulatory cells are negatively correlated with the overall survival of hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Yang An, Song Gao, Wen-Chao Zhao, Bao-An Qiu, Nian-Xin Xia, Peng-Jun Zhang and Zhen-Ping Fan
ORCID
Author(s) ORCID Number
Yang An http://orcid.org/0000-0002-2515-4562
Song Gao http://orcid.org/0000-0002-7466-3654
Wen-Chao Zhao http://orcid.org/0000-0002-1445-376X
Bao-An Qiu http://orcid.org/0000-0001-9474-3101
Nian-Xin Xia http://orcid.org/0000-0002-3785-1381
Peng-Jun Zhang http://orcid.org/0000-0002-7391-2495
Zhen-Ping Fan http://orcid.org/0000-0001-5725-5758
Funding Agency and Grant Number
Funding Agency Grant Number
National Key R&D Program of China 2016YFC0106604
National Natural Science Foundation of China 81502591
Corresponding Author Zhen-Ping Fan, MD, Doctor, The Liver Disease Center for Cadre Medical Care, Beijing 302 Military Hospital, Xi Si Huan Zhong Road 100, Beijing 100039, China. fanzp302@126.com
Key Words Hepatocellular carcinoma; Transforming growth factor-β; Regulatory cells; Peripheral blood mononuclear cells; Interleukin-6
Core Tip We aimed to understand the cellular and molecular changes in peripheral blood of hepatocellular carcinoma (HCC) and provide new methods for its diagnosis and treatment. The results showed that transforming growth factor-β (TGF-β) may promote tumor growth and proliferation by inducing the production of interleukin-6, and TGF-β and TGF-β+ regulatory cells may serve as new markers for predicting poor prognosis of HCC.
Publish Date 2018-07-05 01:33
Citation An Y, Gao S, Zhao WC, Qiu BA, Xia NX, Zhang PJ, Fan ZP. Transforming growth factor-β and peripheral regulatory cells are negatively correlated with the overall survival of hepatocellular carcinoma. World J Gastroenterol 2018; 24(25): 2733-2740
URL http://www.wjgnet.com/1007-9327/full/v24/i25/2733.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i25.2733
Full Article (PDF) WJG-24-2733.pdf
Full Article (Word) WJG-24-2733.doc
STROBE Statement 38908-STROBE statement.pdf
Manuscript File 38908-Review.docx
Answering Reviewers 38908-Answering reviewers.pdf
Audio Core Tip 38908-Audio core tip.m4a
Biostatistics Review Certificate 38908-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 38908-Conflict-of-interest statement.pdf
Copyright License Agreement 38908-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 38908-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 38908-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 38908-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 38908-Language certificate.pdf
Peer-review Report 38908-Peer-review(s).pdf
Scientific Misconduct Check 38908-Scientific misconduct check.pdf
Scientific Editor Work List 38908-Scientific editor work list.pdf