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Articles Published Processes
5/18/2018 2:03:19 AM | Browse: 1102 | Download: 1319
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Received |
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2018-03-29 10:14 |
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Peer-Review Started |
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2018-03-30 06:35 |
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To Make the First Decision |
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2018-04-27 02:07 |
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Return for Revision |
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2018-04-27 03:50 |
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Revised |
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2018-05-03 13:20 |
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Second Decision |
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2018-05-10 09:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-05-11 04:51 |
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Articles in Press |
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2018-05-11 04:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-05-17 00:58 |
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Publish the Manuscript Online |
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2018-05-18 02:03 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Role of osteoprotegerin/receptor activator of nuclear factor kappa B/receptor activator of nuclear factor kappa B ligand axis in nonalcoholic fatty liver disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Lucia Pacifico, Gian Marco Andreoli, Miriam D'Avanzo, Delia De Mitri and Pasquale Pierimarchi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lucia Pacifico, MD, Associate Professor, oliclinico Umberto I Hospital, Sapienza University of Rome, Sapienza University of Rome, Rome 00161, Italy. lucia.pacifico@uniroma1.it |
| Key Words |
Nonalcoholic fatty liver disease; Insulin resistance; Metabolic syndrome; Osteoprotegerin; Receptor activator of nuclear factor kappa B; Receptor activator of nuclear factor kappa B ligand |
| Core Tip |
Recently, epidemiological studies have linked obesity, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD) to decreased bone mineral density and osteoporosis, highlighting an intricate interplay among bone, adipose tissue, and liver. Osteoprotegerin (OPG), an important symbol of the receptor activator of nuclear factor-B ligand/receptor activator of nuclear factor kappa B/OPG axis activation, has recently been suggested to have critical roles in the initiation and perpetuation of obesity-related comorbidities including NAFLD. The available studies have reported either positive or negative associations between OPG and NAFLD. Thus, more research is needed to clarify its role in this liver disease. |
| Publish Date |
2018-05-18 02:03 |
| Citation |
Pacifico L, Andreoli GM, D’Avanzo M, De Mitri D, Pierimarchi P. Role of osteoprotegerin/receptor activator of nuclear factor kappa B/receptor activator of nuclear factor kappa B ligand axis in nonalcoholic fatty liver disease. World J Gastroenterol 2018; 24(19): 2073-2082 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i19/2073.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i19.2073 |
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