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Articles Published Processes
10/27/2018 4:40:10 AM | Browse: 977 | Download: 1329
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Received |
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2018-03-29 00:16 |
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Peer-Review Started |
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2018-03-29 09:25 |
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To Make the First Decision |
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2018-05-11 01:12 |
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Return for Revision |
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2018-05-15 00:49 |
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Revised |
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2018-05-30 10:38 |
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Second Decision |
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2018-07-06 09:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-07-10 22:57 |
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Articles in Press |
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2018-07-10 22:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-10-19 00:13 |
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Publish the Manuscript Online |
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2018-10-27 04:40 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Dental pulp cell bank as a possible future source of individual hepatocytes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shogo Ohkoshi, Haruka Hirono, Taka Nakahara and Hiroshi Ishikawa |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science |
No. 17K08966 (to Ohkoshi S) |
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| Corresponding Author |
Shogo Ohkoshi, MD, PhD, Professor, Department of Internal Medicine, School of Life Dentistry at Niigata, the Nippon Dental University, 1-8 Hamaura-Cho, Chuo-ku, Niigata 951-8580, Japan. okoshi@ngt.ndu.ac.jp |
| Key Words |
Mesenchymal stem cells; Stem cells from human exfoliating teeth; Hepatocytes; dental pulp cell bank; Liver diseases |
| Core Tip |
Dental pulp-origin mesenchymal stem cells have a remarkable potential for regenerative medicine in both differentiation and proliferation capacity. Dental pulp cell banks are currently under operation in several institutions in Japan, as they can be obtained easily and less invasively in the personal growth process. Recent findings that they can differentiate into hepatocytes suggest that they can be applied to refractory liver diseases as either auto or allogenic cell therapies. These hepatocytes can be used as tailor-made components for a bioartificial liver or liver-on-a-chip to screen for drug toxicities in preparation for future use. |
| Publish Date |
2018-10-27 04:40 |
| Citation |
Ohkoshi S, Hirono H, Nakahara T, Ishikawa H. Dental pulp cell bank as a possible future source of individual hepatocytes. World J Hepatol 2018; 10(10): 702-707 |
| URL |
http://www.wjgnet.com/1948-5182/full/v10/i10/702.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v10.i10.702 |
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