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6/4/2018 7:22:04 AM | Browse: 1018 | Download: 1575
Publication Name World Journal of Gastroenterology
Manuscript ID 39052
Country/Territory China
Received
2018-03-28 03:34
Peer-Review Started
2018-03-28 11:49
To Make the First Decision
2018-04-19 01:08
Return for Revision
2018-04-21 07:35
Revised
2018-04-28 01:30
Second Decision
2018-05-04 09:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-05-05 23:52
Articles in Press
2018-05-05 23:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-05-21 19:37
Typeset the Manuscript
2018-06-01 04:09
Publish the Manuscript Online
2018-06-04 07:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author (s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Acute kidney injury in acute-on-chronic liver failure is different from in decompensated cirrhosis
Manuscript Source Unsolicited Manuscript
All Author List Qun-Qun Jiang, Mei-Fang Han, Ke Ma, Guang Chen, Xiao-Yang Wan, Semvua Bukheti Kilonzo, Wen-Yu Wu, Yong-Li Wang, Jie You and Qin Ning
ORCID
Author(s) ORCID Number
Qun-Qun Jiang http://orcid.org/0000-0001-7271-4975
Mei-Fang Han http://orcid.org/0000-0002-1948-8128
Ke Ma http://orcid.org/0000-0003-1436-3673
Guang Chen http://orcid.org/0000-0002-9964-373X
Xiao-Yang Wan http://orcid.org/0000-0002-8871-2015
Semvua Bukheti Kilonzo http://orcid.org/0000-0003-1197-9368
Wen-Yu Wu http://orcid.org/0000-0002-8507-1806
Yong-Li Wang http://orcid.org/0000-0002-5278-9395
Jie You http://orcid.org/0000-0001-8116-8902
Qin Ning http://orcid.org/0000-0002-2027-9593
Funding Agency and Grant Number
Funding Agency Grant Number
Innovation Team Development Plan of the Ministry of Education IRT 14R20
National Natural Science Foundation of China 81571989
Corresponding Author Qin Ning, MD, PhD, Professor, Department and institute of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China. qning@vip.sina.com
Key Words Decompensated cirrhosis; Acute-on-chronic liver failure; Acute kidney injury; Biomarker; Etiology; Treatment; Prognosis
Core Tip Acute kidney injury (AKI) is common in acute-on-chronic liver failure (ACLF) and decompensated cirrhosis (DC) patients. Though ACLF and DC have been identified as two different diseases, the difference in AKI between these two diseases is rarely studied, and whether AKI should be handled in the same way in both diseases is still uncertain. This study combined multiple tubular injury biomarkers and has shown that AKI in patients with ACLF is distinctly different from in DC patients. AKI in ACLF patients is more likely to be caused by structural damage, and tends to be more progressive, with poorer response to terlipressin treatment and a worse prognosis.
Publish Date 2018-06-04 07:22
Citation Jiang QQ, Han MF, Ma K, Chen G, Wan XY, Kilonzo SB, Wu WY, Wang YL, You J, Ning Q. Acute kidney injury in acute-on-chronic liver failure is different from in decompensated cirrhosis. World J Gastroenterol 2018; 24(21): 2300-2310
URL http://www.wjgnet.com/1007-9327/full/v24/i21/2300.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i21.2300
Full Article (PDF) WJG-24-2300.pdf
Full Article (Word) WJG-24-2300.doc
Manuscript File 39052-Review.docx
Answering Reviewers 39052-Answering reviewers.pdf
Audio Core Tip 39052-Audio core tip.mp3
Biostatistics Review Certificate 39052-Biostatistics statement.pdf
Clinical Trial Registration Statement 39052-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 39052-Conflict-of-interest statement.pdf
Copyright License Agreement 39052-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 39052-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 39052-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 39052-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 39052-Language certificate.pdf
Peer-review Report 39052-Peer-review(s).pdf
Scientific Misconduct Check 39052-Scientific misconduct check.pdf
Scientific Editor Work List 39052-Scientific editor work list.pdf