Publication Name	World Journal of Cardiology
Manuscript ID	39060
Country	Chile

Received	2018-03-28 01:24
Peer-Review Started	2018-03-28 09:19
To Make the First Decision	2018-04-11 01:25
Return for Revision	2018-04-13 02:59
Revised	2018-04-27 21:22
Second Decision	2018-05-09 09:26
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-05-10 23:00
Articles in Press	2018-05-10 23:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-09-29 09:14
Publish the Manuscript Online	2018-09-30 06:52

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Review
Article Title	Myocardial reperfusion injury and oxidative stress: Therapeutic opportunities
Manuscript Source	Invited Manuscript
All Author List	Jaime González-Montero, Roberto Brito, Abraham IJ Gajardo and Ramón Rodrigo
ORCID	Author(s) ORCID Number Jaime González-Montero http://orcid.org/0000-0003-0324-2948 Roberto Brito http://orcid.org/0000-0001-8205-1984 Abraham IJ Gajardo http://orcid.org/0000-0002-6387-3779 Ramón Rodrigo http://orcid.org/0000-0003-1724-571X
Funding Agency and Grant Number	Funding Agency Grant Number FONDEF ID15I10285
Corresponding Author	Ramón Rodrigo, Doctor, Doctor, Molecular and Clinical Pharmacology Program, Institute of Biomedical Sciences, Faculty of Medicine,, University of Chile, Independencia 1027,, Santiago 70058, Chile. rrodrigo@med.uchile.cl
Key Words	Acute myocardial infarction; Repefusion injury; Oxidative stress; Ascorbate; N-acetylcysteine; Deferoxamine
Core Tip	Acute myocardial infarction is the leading cause of death in the world. At least half of the resulting myocardial damage is associated with myocardial reperfusion. Myocardial reperfusion injury is associated with reactive oxygen species production and iron mobilization. Treatment with antioxidants such as ascorbate, N-acetylcysteine, and an iron chelator such as deferox¬amine, could prevent the development of this damage.
Publish Date	2018-09-30 06:52
Citation	González-Montero J, Brito R, Gajardo AIJ, Rodrigo R. Myocardial reperfusion injury and oxidative stress: Therapeutic opportunities. World J Cardiol 2018; 10(9): 74-86
URL	http://www.wjgnet.com/1949-8462/full/v10/i9/74.htm
DOI	http://dx.doi.org/10.4330/wjc.v10.i9.74

Full Article (PDF)	WJC-10-74.pdf
Full Article (Word)	WJC-10-74.doc
Manuscript File	39060-Review.doc
Answering Reviewers	39060-Answering reviewers.pdf
Audio Core Tip	39060-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39060-Conflict-of-interest statement.pdf
Copyright License Agreement	39060-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	39060-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	39060-Language certificate.pdf
Supplementary Material	39060-Supplementary-Material-revision.pdf
Peer-review Report	39060-Peer-review(s).pdf
Scientific Editor Work List	39060-Scientific editor work list.pdf