Publication Name	World Journal of Gastroenterology
Manuscript ID	39118
Country	France

Received	2018-04-07 10:17
Peer-Review Started	2018-04-07 13:56
To Make the First Decision	2018-04-27 02:26
Return for Revision	2018-04-27 08:39
Revised	2018-05-03 08:54
Second Decision	2018-05-17 09:30
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-05-18 01:39
Articles in Press	2018-05-18 01:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-05-31 06:29
Publish the Manuscript Online	2018-06-11 01:12

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Microbial markers in colorectal cancer detection and/or prognosis
Manuscript Source	Invited Manuscript
All Author List	Romain Villéger, Amélie Lopes, Julie Veziant, Johan Gagniere, Nicolas Barnich, Elisabeth Billard, Delphine Boucher and Mathilde Bonnet
ORCID	Author(s) ORCID Number Romain Villéger http://orcid.org/0000-0003-2815-045X Amélie Lopes http://orcid.org/0000-0001-8959-7840 Julie Veziant http://orcid.org/0000-0001-5247-461X Johan Gagniere http://orcid.org/0000-0002-1820-3362 Nicolas Barnich http://orcid.org/0000-0001-9465-7844 Elisabeth Billard http://orcid.org/0000-0002-6066-4584 Delphine Boucher http://orcid.org/0000-0002-6979-4094 Mathilde Bonnet http://orcid.org/0000-0003-3629-7267
Funding Agency and Grant Number	Funding Agency Grant Number Inserm and Université Clermont Auvergne (UMR 1071), INRA USC-2018 “Conseil regional Auvergne-Rhones-Alpes”and FDER/CPER
Corresponding Author	Mathilde Bonnet, PhD, Assistant Professor, M2iSH “Microbes, intestin, inflammation et Susceptibilité de l’Hôte” UMR 1071 Inserm/Université d’Auvergne USC INRA 2018, Centre Biomédical de Recherche et Valorisation, 28 Place Henri Dunant, Clermont-Ferrand 63000, France. mathilde.bonnet@uca.fr
Key Words	Colorectal cancer; microbiota; F. nucleatum; Colibactin-producing E. coli; prognostic markers; diagnostic markers; dysbiosis
Core Tip	Many clinical studies have reported a disruption in the gut microbiota balance and in the faecal meta­bolome in colorectal cancer. In this review, we describe the modifications in the microbiota composition and metabolome observed in colorectal cancer (CRC) tissue and stool samples. Then, we detail how these microbiota modifications may represent novel and promising non-invasive diagnostic and/or prognostic markers for CRC and advanced adenoma.
Publish Date	2018-06-11 01:12
Citation	Villéger R, Lopès A, Veziant J, Gagnière J, Barnich N, Billard E, Boucher D, Bonnet M. Microbial markers in colorectal cancer detection and/or prognosis. World J Gastroenterol 2018; 24(22): 2327-2347
URL	http://www.wjgnet.com/1007-9327/full/v24/i22/2327.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i22.2327

Full Article (PDF)	WJG-24-2327.pdf
Manuscript File	39118-Review.docx
Answering Reviewers	39118-Answering reviewers.pdf
Audio Core Tip	39118-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39118-Conflict-of-interest statement.pdf
Copyright License Agreement	39118-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	39118-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	39118-Language certificate.pdf
Peer-review Report	39118-Peer-review(s).pdf
Scientific Misconduct Check	39118-Scientific misconduct check.pdf
Scientific Editor Work List	39118-Scientific editor work list.pdf