Publication Name	World Journal of Hepatology
Manuscript ID	39128
Country	Romania

Received	2018-03-29 02:56
Peer-Review Started	2018-03-29 10:10
To Make the First Decision	2018-05-14 09:14
Return for Revision	2018-05-15 00:14
Revised	2018-05-29 15:55
Second Decision	2018-06-25 11:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-06-27 06:32
Articles in Press	2018-06-27 06:32
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-07-02 20:42
Typeset the Manuscript	2018-07-24 06:12
Publish the Manuscript Online	2018-07-27 16:31

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Contemporary role of liver biopsy in hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Zeno Sparchez and Tudor Mocan
ORCID	Author(s) ORCID Number Zeno Sparchez http://orcid.org/0000-0002-3813-1677 Tudor Mocan http://orcid.org/0000-0001-7785-6403
Funding Agency and Grant Number
Corresponding Author	Tudor Mocan, MD, Manager, Doctor, Doctor, 3rd Medical Department, Institute for Gastroenterology and Hepatology, Iuliu Hatieganu University of Medicine and Pharmacy, Croitorilor st. 19-21, Cluj-Napoca 400162, Romania. mocan_tudor@yahoo.com
Key Words	Molecular classification; Bleeding; Seeding; Liver biopsy; Hepatocellular carcinoma
Core Tip	We now face a time when oncology is moving towards personalized medicine. The development of high-throughput molecular technologies has allowed us to define the main molecular mechanism involved in hepatocellular carcinoma (HCC) development and progr­ession. Several subtypes of HCC have been described using both molecular and histological characterization. In the context of histological HCC sub-classes, each wi­th distinct molecular patterns and prognostic impacts, the need for liver biopsy in HCC management becomes a necessity. In this era of personalized medicine, knowing the strengths of each sampling technique is of the utmost importance.
Publish Date	2018-07-27 16:31
Citation	Sparchez Z, Mocan T. contemporary role of liver biopsy in hepatocellular carcinoma. World J Hepatol 2018; 10(7): 452-461
URL	http://www.wjgnet.com/1948-5182/full/v10/i7/452.htm
DOI	http://dx.doi.org/10.4254/wjh.v10.i7.452

Full Article (PDF)	WJH-10-452.pdf
Full Article (Word)	WJH-10-452.doc
Manuscript File	39128-Review.docx
Answering Reviewers	39128-Answering reviewers.pdf
Audio Core Tip	39128-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39128-Conflict-of-interest statement.pdf
Copyright License Agreement	39128-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	39128-Language certificate.pdf
Peer-review Report	39128-Peer-review(s).pdf
Scientific Misconduct Check	39128-Scientific misconduct check.pdf
Scientific Editor Work List	39128-Scientific editor work list.pdf