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Articles Published Processes
9/16/2018 4:04:19 AM | Browse: 1050 | Download: 1942
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Received |
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2018-03-29 04:04 |
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Peer-Review Started |
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2018-03-29 12:59 |
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To Make the First Decision |
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2018-05-02 03:43 |
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Return for Revision |
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2018-05-03 07:16 |
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Revised |
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2018-06-20 12:05 |
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Second Decision |
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2018-06-25 10:21 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-06-27 06:51 |
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Articles in Press |
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2018-06-27 06:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-09-10 08:29 |
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Publish the Manuscript Online |
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2018-09-16 04:04 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Basic Study |
| Article Title |
Vascular endothelial growth factor for the treatment of femoral head osteonecrosis: An experimental study in canines
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zoe H Dailiana, Nikolaos Stefanou, Lubna Khaldi, Georgios Dimakopoulos, James R Bowers, Cristian Fink and James R Urbaniak |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Piedmont Orthopaedic Foundation, United States |
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| Corresponding Author |
Zoe H Dailiana, MD, PhD, Professor, Surgeon, Department of Orthopaedic Surgery, Faculty of Medicine, University of Thessalia, 3 Panepistimiou St., Larissa 41500, Greece. dailiana@med.uth.gr |
| Key Words |
Osteonecrosis; Vascular endothelial growth factor; Avascular necrosis; Femoral head; Osteogenesis; Animal model |
| Core Tip |
Osteonecrosis of the femoral head (ONFH) is a painful disorder which usually results in hip joint destruction. Although the pathogenic process is poorly understood, ON is the final condition that completes an already precarious microcirculation of the FH by traumatic and non-traumatic causes. Since vascular endothelial growth factor (VEGF) regulates numerous cellular events associated with angiogenesis and osteogenesis, we evaluated, in an experimental model of ONFH in canines if the local treatment with VEGF leads to bone tissue remodeling and new bone formation at the necrotic site, and subsequently to reversal of ON. |
| Publish Date |
2018-09-16 04:04 |
| Citation |
Dailiana ZH, Stefanou N, Khaldi L, Dimakopoulos G, Bowers JR, Fink C, Urbaniak JR. Vascular endothelial growth factor for the treatment of femoral head osteonecrosis: An experimental study in canines. World J Orthop 2018; 9(9): 120-129 |
| URL |
http://www.wjgnet.com/2218-5836/full/v9/i9/120.htm |
| DOI |
http://dx.doi.org/10.5312/wjo.v9.i9.120 |
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