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Articles Published Processes
5/28/2018 9:41:37 AM | Browse: 975 | Download: 1599
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Received |
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2018-03-29 10:16 |
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Peer-Review Started |
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2018-03-30 08:15 |
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To Make the First Decision |
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2018-04-11 07:18 |
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Return for Revision |
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2018-04-13 07:34 |
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Revised |
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2018-04-19 13:06 |
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Second Decision |
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2018-04-23 05:31 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-04-23 16:29 |
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Articles in Press |
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2018-04-23 16:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-05-14 21:29 |
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Typeset the Manuscript |
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2018-05-17 01:03 |
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Publish the Manuscript Online |
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2018-05-28 09:41 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Effects of hepatitis E virus infection on interferon production via ISG15
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Min Wang, Ying Huang, Man He, Wen-Ju Peng and De-Ying Tian |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
81570540 |
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| Corresponding Author |
De-Ying Tian, PhD, Professor, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan 430030, Hubei Province, China. dytian@tjh.tjmu.edu.cn |
| Key Words |
Open reading frame 3; Interferon-stimulated gene 15; Interferon-alpha; Hepatitis E virus; Interferon-beta |
| Core Tip |
To date, few studies have investigated the role of ISG15 in hepatitis E virus (HEV) infection and the impact of ISG15 on interferons (IFN) production. This study showed that HEV could inhibit the level of type Ⅰ IFN through regulating the expression of IFN-stimulated gene (ISG)15, which may attenuate the IFN response, allowing for successful infection of their hosts. The present study enhances the understanding of the interaction between ISG15 and HEV in the host innate immune response, which may provide useful insight for the development of new antiviral drugs and antiviral strategies. |
| Publish Date |
2018-05-28 09:41 |
| Citation |
Wang M, Huang Y, He M, Peng WJ, Tian DY. Effects of hepatitis E virus infection on interferon production via ISG15. World J Gastroenterol 2018; 24(20): 2173-2180 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i20/2173.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i20.2173 |
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