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Articles Published Processes
7/27/2018 6:43:44 AM | Browse: 1149 | Download: 1873
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Received |
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2018-04-17 00:31 |
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Peer-Review Started |
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2018-04-17 16:26 |
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To Make the First Decision |
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2018-05-23 06:12 |
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Return for Revision |
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2018-06-11 09:00 |
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Revised |
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2018-06-17 08:14 |
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Second Decision |
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2018-06-27 09:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-06-27 17:30 |
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Articles in Press |
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2018-06-27 17:30 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-07-07 17:31 |
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Typeset the Manuscript |
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2018-07-25 03:14 |
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Publish the Manuscript Online |
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2018-07-27 06:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Franz-Tassilo Müller-Graff, Brit Fitzner, Robert Jaster, Brigitte Vollmar and Dietmar Zechner |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Deutsche Forschungsgemeinschaft (DFG research group FOR 2591) |
No. 321137804, ZE 712/1-1 and VO 450/15-1 |
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| Corresponding Author |
Dietmar Zechner, PhD, Academic Research, Senior Scientist, Institute for Experimental Surgery, Rostock University Medical Center, Schillingallee 69a, Rostock 18057, Germany. dietmar.zechner@uni-rostock.de |
| Key Words |
Autoimmune disease; Diabetes; Treg; FoxP3; Autoimmune pancreatitis; MRL/MpJ mice |
| Core Tip |
Temporary or sustained hyperglycemia can be observed in about 42%-66% of patients with autoimmune pancreatitis. However, it is unknown to what extent hyperglycemia has an influence on the course of this disease. This preclinical study demonstrates that hyperglycemia does not lead to an aggravation but rather an attenuation of autoimmune pancreatitis. Thus, this result might have the clinical implication that a tight adjustment of blood glucose concentration in patients with autoimmune pancreatitis is not needed, because it might not have a beneficial effect on the progression of this disease. |
| Publish Date |
2018-07-27 06:43 |
| Citation |
Müller-Graff FT, Fitzner B, Jaster R, Vollmar B, Zechner D. Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells. World J Gastroenterol 2018; 24(28): 3120-3129 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i28/3120.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i28.3120 |
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