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Articles Published Processes
6/15/2018 9:13:16 AM | Browse: 1179 | Download: 1127
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Received |
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2018-04-13 05:54 |
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Peer-Review Started |
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2018-04-13 06:51 |
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To Make the First Decision |
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2018-04-27 02:10 |
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Return for Revision |
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2018-04-27 07:04 |
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Revised |
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2018-05-08 14:32 |
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Second Decision |
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2018-06-01 09:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-06-01 18:24 |
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Articles in Press |
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2018-06-01 18:24 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-06-13 08:43 |
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Publish the Manuscript Online |
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2018-06-15 09:13 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Taking advantage of the potential of mesenchymal stromal cells in liver regeneration: Cells and extracellular vesicles as therapeutic strategies
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Manuscript Source |
Invited Manuscript |
All Author List |
Esteban Juan Fiore, Luciana María Dominguez, Juan Bayo, Mariana Gabriela Garcia and Guillermo Mazzolini |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Guillermo Mazzolini, MD, PhD, Professor, Laboratory of Gene Therapy, Instituto de Investigaciones en Medicina Traslacional, CONICET-Universidad Austral, Av. Pte. Perón 1500 (B1629AHJ), Derqui-Pilar 999071, Buenos Aires, Argentina. gmazzoli@cas.austral.edu.ar |
Key Words |
Mesenchymal stem cells; Extracellular vesicles; Cirrhosis; Liver; Acute damage; Regeneration |
Core Tip |
Cell-based therapies for acute and chronic liver diseases are very attractive strategies. In particular, mesenchymal stem/stromal cells (MSCs) are multipotent cells able to induce protective and pro-regenerative effects in different liver diseases. The mechanism through which MSCs support tissue regeneration is via secretion of paracrine factors, and solid evidence supports that part of these effects is mediated by extracellular vesicles (EVs). Therefore, EVs have become an attractive option in the research for new treatments in liver diseases. |
Publish Date |
2018-06-15 09:13 |
Citation |
Fiore EJ, Domínguez LM, Bayo J, García MG, Mazzolini GD. Taking advantage of the potential of mesenchymal stromal cells in liver regeneration: Cells and extracellular vesicles as therapeutic strategies. World J Gastroenterol 2018; 24(23): 2427-2440 |
URL |
http://www.wjgnet.com/1007-9327/full/v24/i23/2427.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v24.i23.2427 |
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