Publication Name	World Journal of Gastroenterology
Manuscript ID	39323
Country	Italy

Received	2018-04-12 23:32
Peer-Review Started	2018-04-13 01:23
To Make the First Decision	2018-04-27 02:09
Return for Revision	2018-04-27 07:14
Revised	2018-05-16 12:16
Second Decision	2018-05-24 08:17
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-05-28 05:01
Articles in Press	2018-05-28 05:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-06-04 10:54
Publish the Manuscript Online	2018-06-11 01:12

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Treatment of Helicobacter pylori infection in atrophic gastritis
Manuscript Source	Invited Manuscript
All Author List	Edith Lahner, Marilia Carabotti and Bruno Annibale
ORCID	Author(s) ORCID Number Edith Lahner http://orcid.org/0000-0002-9503-8639 Marilia Carabotti http://orcid.org/0000-0001-9984-4630 Bruno Annibale http://orcid.org/0000-0001-9120-5957
Funding Agency and Grant Number
Corresponding Author	Bruno Annibale, MD, PhD, Full Professor, Medical-Surgical Department of Clinical Sciences and Translational Medicine, Sapienza University of Rome, Via Grottarossa 1035, Rome 00189, Italy. bruno.annibale@uniroma1.it
Key Words	Atrophic gastritis; Preneoplastic condition; Intestinal metaplasia; Helicobacter pylori; Eradication treatment
Core Tip	Atrophic gastritis (AG) may arise from long-standing Helicobacter pylori (Hp) infection and is linked to increased gastric cancer risk. According to guidelines, Hp-positive AG patients should receive eradication treat­ment. The goals of treatment are as follows: (1) Cure of infection, (2) possible reversal of atrophic/metaplastic changes, and (3) prevention of gastric cancer. When involving the corporal mucosa, AG is linked to reduced acid secretion. At a non-acidic intra-gastric pH, the ef­ficacy of common treatment regimens may not be the same as those observed in an acid-producing stomach. There is a paucity of evidence of efficacy of eradication regimens in AG patients. Bismuth-based therapies may be promising.
Publish Date	2018-06-11 01:12
Citation	Lahner E, Carabotti M, Annibale B. Treatment of Helicobacter pylori infection in atrophic gastritis. World J Gastroenterol 2018; 24(22): 2373-2380
URL	http://www.wjgnet.com/1007-9327/full/v24/i22/2373.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i22.2373

Full Article (PDF)	WJG-24-2373.pdf
Manuscript File	39323-Review.docx
Answering Reviewers	39323-Answering reviewers.pdf
Audio Core Tip	39323-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39323-Conflict-of-interest statement.pdf
Copyright License Agreement	39323-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	39323-Language certificate.pdf
Peer-review Report	39323-Peer-review(s).pdf
Scientific Misconduct Check	39323-Scientific misconduct check.pdf
Scientific Editor Work List	39323-Scientific editor work list.pdf