ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
his article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Prognostic significance of the fibrinogen-to-albumin ratio in gallbladder cancer patients
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Wei-Yu Xu, Hao-Hai Zhang, Jian-Ping Xiong, Xiao-Bo Yang, Yi Bai, Jian-Zhen Lin, Jun-Yu Long, Yong-Chang Zheng, Hai-Tao Zhao and Xin-Ting Sang |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National key project research and development projects |
S2016G9012 |
International Science and Technology Cooperation Projects |
2015DFA30650 |
The Capital Special Research Project for Clinical Application |
Z151100004015170 |
|
Corresponding Author |
Xin-Ting Sang, MD, Professor, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1Shuaifuyuan, Wangfujing, Beijing 100730, China. sangxt@pumch.cn |
Key Words |
Gallbladder cancer; Fibrinogen; Albumin; Fibrinogen-to-albumin ratio; Prognosis; Survival |
Core Tip |
The vital prognostic significance of fibrinogen and serum albumin has been confirmed in diverse malignancies, presenting host hemostasis and nutrition, respectively. Moreover, elevated plasma fibrinogen and reduced serum albumin levels are significantly related to shortened survival of cancer patients. It is reported that fibrinogen-to-albumin ratio (FAR) is more potent in predicting cancer patient prognosis than elevated fibrinogen or reduced serum albumin level alone. Nevertheless, there has been no study on the prognostic role of FAR in gallbladder cancer (GBC). Herein, we defined an elevated preoperative FAR, featured by noninvasiveness, cost-effectiveness and easily-accessible, which was a potential prognostic indicator for GBC. |
Publish Date |
2018-08-03 11:25 |
Citation |
Xu WY, Zhang HH, Xiong JP, Yang XB, Bai Y, Lin JZ, Long JY, Zheng YC, Zhao HT, Sang XT. Prognostic significance of the fibrinogen-to-albumin ratio in gallbladder cancer patients. World J Gastroenterol 2018; 24(29): 3281-3292 |
URL |
http://www.wjgnet.com/1007-9327/full/v24/i29/3281.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v24.i29.3281 |