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Articles Published Processes
9/7/2018 1:56:18 AM | Browse: 961 | Download: 1442
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Received |
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2018-04-27 08:35 |
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Peer-Review Started |
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2018-04-27 09:26 |
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To Make the First Decision |
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2018-06-15 02:44 |
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Return for Revision |
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2018-06-15 03:27 |
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Revised |
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2018-06-23 16:12 |
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Second Decision |
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2018-07-26 14:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-08-01 13:54 |
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Articles in Press |
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2018-08-01 13:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-08-07 18:15 |
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Typeset the Manuscript |
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2018-09-02 09:01 |
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Publish the Manuscript Online |
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2018-09-07 01:56 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Impact of sorafenib on epidural fibrosis: An immunohistochemical study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Osman Tanriverdi, Uzay Erdogan, Canan Tanik, Ilhan Yilmaz, Omur Gunaldi, Huseyin Utku Adilay, Ayca Arslanhan and Metehan Eseoglu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Osman Tanriverdi, MD, Doctor, Doctor, Department of Neurosurgery and Psychiatry, University of Health Sciences, Bakırköy Prof. Dr. Mazhar Osman Training and Research Hospital for Neurology, Tevfik sağlam cad. No. 1, İstanbul 34303, Türkiye. osmantanriverdi74@gmail.com |
| Key Words |
Vascular endothelial growth factor; CD105; Osteopontin; Sorafenib; Spinal epidural fibrosis |
| Core Tip |
This study addressed the prevention of spinal epidural fibrosis (EF) by sorafenib, an antineoplastic agent, though immunohistochemical analyses of EF as a consequence of laminectomy in rats. The study demonstrated for the first time that the fibrosis thickness, inflammatory cell density, arachnoid adherences, fibrosis scores, and vessel count were significantly lower in the treatment group. These findings indicate that locally administered sorafenib may help reduce spinal EF after laminectomy without any significant complications or side effects. |
| Publish Date |
2018-09-07 01:56 |
| Citation |
Tanriverdi O, Erdogan U, Tanik C, Yilmaz I, Gunaldi O, Adilay HU, Arslanhan A, Eseoglu M. Impact of sorafenib on epidural fibrosis: An immunohistochemical study. World J Clin Cases 2018; 6(9): 249-258 |
| URL |
http://www.wjgnet.com/2307-8960/full/v6/i9/249.htm |
| DOI |
http://dx.doi.org/10.12998/wjcc.v6.i9.249 |
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