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8/17/2018 10:48:34 AM | Browse: 204 | Download: 115
Publication Name World Journal of Gastroenterology
Manuscript ID 39576
Country of Manuscript Source China
Received
2018-05-03 10:30
Peer-Review Started
2018-05-04 03:44
To Make the First Decision
2018-05-23 06:15
Return for Revision
2018-05-25 11:17
Revised
2018-06-01 07:48
Second Decision
2018-06-25 11:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-06-25 18:46
Articles in Press
2018-06-25 18:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-07-02 20:40
Typeset the Manuscript
2018-08-16 06:54
Publish the Manuscript Online
2018-08-17 10:48
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Virology
Manuscript Type Review
Article Title Hepatitis B virus infection: defective surface antigen expression and pathogenesis
Manuscript Source Invited Manuscript
All Author List Chun-Chen Wu, Ying-Shan Chen, Liang Cao, Xin-Wen Chen and Meng-Ji Lu
ORCID
Author(s) ORCID Number
Chun-Chen Wu http://orcid.org/0000-0002-6888-213X
Ying-Shan Chen http://orcid.org/0000-0002-2276-4496
Liang Cao http://orcid.org/0000-0001-5974-9815​
Xin-Wen Chen http://orcid.org/0000-0002-4052-8155
Meng-Ji Lu http://orcid.org/0000-0003-4287-9941
Funding Agency and Grant Number
Funding Agency Grant Number
National Nature Science Foundation of China 31770180
the Youth Innovation Promotion Association CAS 201603
Corresponding author Meng-Ji Lu, PhD, Professor, Institute of Virology, University Hospital of Essen, Hufelandstrasse 55, Essen 45122, Germany. Mengji.lu@uni-due.de
Keywords Hepatitis B surface protein; Defective surface antigen mutants; Endoplasmic reticulum stress; Fulminant hepatitis B; Occult hepatitis B virus infection; Pathogenesis
Core Tip Defective surface antigen mutation is a type of mutation with great clinical relevance. Many previous publications have explored the association of defective surface antigen mutation with the development of hepatitis B virus (HBV)-associated hepatocellular carcinoma. However, there are no reviews available that elaborate on the relationship between defective surface antigen mutation and HBV-associated fulminant hepatitis (FH), as well as occult hepatitis B virus infection (OBI). This review will focus on these two aspects to discuss the nature of defective HBV surface antigen mutations and their contribution to the pathogenesis of FH. The relationship between defective surface antigens and OBI are also discussed.
Publish Date 2018-08-17 10:48
Citation Wu CC, Chen YS, Cao L, Chen XW, Lu MJ. Hepatitis B virus infection: defective surface antigen expression and pathogenesis. World J Gastroenterol 2018; 24(31): 3488-3499
Url http://www.wjgnet.com/1007-9327/full/v24/i31/3488.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i31.3488
Full Article (PDF) WJG-24-3488.pdf
Full Article (Word) WJG-24-3488.doc
Manuscript File 39576-Review.docx
Answering Reviewers 39576-Answering reviewers.pdf
Audio Core Tip 39576-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 39576-Conflict-of-interest statement.pdf
Copyright License Agreement 39576-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 39576-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 39576-Language certificate.pdf
Peer-review Report 39576-Peer-review(s).pdf
Scientific Misconduct Check 39576-Scientific misconduct check.pdf
Scientific Editor Work List 39576-Scientific editor work list.pdf