Publication Name	World Journal of Gastroenterology
Manuscript ID	39588
Country	Poland

Received	2018-04-28 01:22
Peer-Review Started	2018-04-28 14:41
To Make the First Decision	2018-06-06 02:08
Return for Revision	2018-06-11 07:46
Revised	2018-06-25 13:44
Second Decision	2018-06-29 11:32
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-06-30 02:22
Articles in Press	2018-06-30 02:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-08-08 03:10
Publish the Manuscript Online	2018-08-13 07:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Minireviews
Article Title	Form confers function: Case of the 3’X region of the hepatitis C virus genome
Manuscript Source	Invited Manuscript
All Author List	Mariola Dutkiewicz and Jerzy Ciesiolka
ORCID	Author(s) ORCID Number Mariola Dutkiewicz http://orcid.org/0000-0003-1098-0308 Jerzy Ciesiolka http://orcid.org/0000-0001-7274-0751
Funding Agency and Grant Number	Funding Agency Grant Number Foundation for Polish Science POMOST/2013-8/5 Polish Ministry of Science and Higher Education KNOW
Corresponding Author	Mariola Dutkiewicz, PhD, Associate Professor, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, Poznan 61-704, Poland. mariolad@ibch.poznan.pl
Key Words	Hepatitis C virus; 3’UTR; 3’X-tail; 3’X region; 3’X RNA; RNA structure
Core Tip	Several different secondary structure models of the 3’X region have been proposed. It is likely that the 3’X region adopts more than one structural form in infected cells and that a specific equilibrium between the various forms regulates several aspects of the viral life cycle. This article summarizes current knowledge of the structure and function of the 3’X region of hepatitis C genomic RNA, reviews previous opinions, presents new hypotheses and summarizes the questions that still remain unanswered.
Publish Date	2018-08-13 07:45
Citation	Dutkiewicz M, Ciesiołka J. Form confers function: Case of the 3’X region of the hepatitis C virus genome. World J Gastroenterol 2018; 24(30): 3374-3383
URL	http://www.wjgnet.com/1007-9327/full/v24/i30/3374.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i30.3374

Full Article (PDF)	WJG-24-3374.pdf
Manuscript File	39588-Review.docx
Answering Reviewers	39588-Answering reviewers.pdf
Audio Core Tip	39588-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39588-Conflict-of-interest statement.pdf
Copyright License Agreement	39588-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	39588-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	39588-Language certificate.pdf
Peer-review Report	39588-Peer-review(s).pdf
Scientific Misconduct Check	39588-Scientific misconduct check.pdf
Scientific Editor Work List	39588-Scientific editor work list.pdf